A rant on Reddit from a male who identifies as a woman complaining that a 999 call handler asked for his sex (described at 'gender assigned at birth') when discussing symptoms.
https://www.reddit.com/r/transgenderUK/comments/1f9cq5s/had_to_just_call_999_as_asthma_was_terrifyingly/
Comments are furious at this 'transphobia'.
I checked, and guess what? Sex has a major impact:
'Asthma is a heterogenous disease, and its prevalence and severity are different in males versus females through various ages. As children, boys have an increased prevalence of asthma. As adults, women have an increased prevalence and severity of asthma. Sex hormones, genetic and epigenetic variations, social and environmental factors, and responses to asthma therapeutics are important factors in the sex differences observed in asthma incidence, prevalence and severity. For women, fluctuations in sex hormone levels during puberty, the menstrual cycle and pregnancy are associated with asthma pathogenesis. Further, sex differences in gene expression and epigenetic modifications and responses to environmental factors, including SARS-CoV-2 infections, are associated with differences in asthma incidence, prevalence and symptoms. '
www.ncbi.nlm.nih.gov/pmc/articles/PMC8783601/
I don't suppose anyone is keeping track of the health impacts on people who don't accurately report their sex when seeking care?