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Weight loss injections should be advertised as lifelong medications

108 replies

weighmoreweighless · 25/04/2026 10:39

When Ozempic first came out, the guidelines were for usage to be for up to 2 years. I can’t remember if I read the rationale for that but seem to recall it was in the guidelines.
Thinking back it was along the lines of Ozempic was to be used alongside lifestyle and psychological support to address unhealthy eating habits and psychological drivers for overeating. By the end of two years people were expected to be able to maintain these new habits and weight. Happy to be corrected there but that’s meet I remember reading.

Now we have Mounjaro and many users are saying it’s a lifelong medication similar to blood pressure medication or asthma medication.

From reading the weight loss injections topic there are lots of posters who believe they will take the drug for a few months and that will be it, cured of obesity.

Now many of those who have successfully lost several stones are saying that they will remain on these drugs for life because of course they stop working once you stop, just like any other medication.

There are plenty of threads from posters who have regained weight after stopping. A few posters say they have maintained their weight loss but these seem rare on mumsnet at least.

I know diets don’t work and wish that word would disappear beyond being used to describe what we eat eg vegetarian diet, Mediterranean diet etc. I’d love to see diet replaced with another word or phrase such as healthier lifestyle or similar.

The reason diets fail, or one of them, is that so many people drastically cut their food intake for a few weeks, struggle with hunger, lose a little weight and give up because it’s too hard to sustain that low level of calories, food and nutrients.

The focus should always be on eating a healthier diet, achieving a healthier lifestyle by including more exercise within your own capabilities, less alcohol, not smoking, plenty of vitamin D, good sleep and relaxation habits. It should be a holistic approach, not just eat less, move more. Eat better and yes, move more but it’s more than that. It’s a mindset of needing to change habits for life. Sure we all have times and events where we eat and drink more or don’t exercise as much for a variety of reasons but what matters is what we do most of the time.

With this in mind I’m thinking that the advertising should be changed to reflect this. Companies need to be more transparent about the medications so that people are fully informed that these drugs are not going to be a quick fix or magic cure like people seem to think or hope. I’d be so angry if I’d paid out thousands to lose weight and then when I stopped it came back on because the prescriber hadn’t been completely open with me. There’s been posters who have stuck to healthier eating and increased exercise but still gained weight after stopping.

There’ll be arguments for fully researching the drugs before taking but how many people have the time or understanding of research to be fully informed? Most will just trust what they read in the press or on social media and the pharmacist prescribing. Critical thinking isn’t applied or rather thinking about what happens after. It’s the instant gratification and not thinking of the long term consequences or the financial implications of having to pay out indefinitely or at least until they become available for all on the NHS. Not unlike that packet of jam doughnuts I really wanted to buy yesterday instead of eating a healthy lunch Confused. Just to clarify I wouldn’t have eaten them all. Two of the five for sure though and maybe a third after the school run. I’m a terrible sugar fiend.

This has ended up all disjointed because I can’t go back up the page to edit as I’m typing. I’ll try once I get to the edit option. I have ADHD and my thought processes are all over the place and I go off on tangents. Sorry.

TL:DR Should pharmaceutical companies/pharmacies/doctors/pharmacists change their advertising and recommendations to say that WLI (weight loss injections/medications) are likely to be needed to be taken for life to control obesity due to the likelihood of weight being regained once stopping even in cases of maintained healthy diet and lifestyle due to the chronic nature of obesity?

I’m going to try and edit this now into some semblance of order but if it remains chaotic I’m sorry. It at least has paragraphs even if it does jump around like a flea at a fair.

Poll:

YABU: No, people who take these drugs should realise that these aren’t a quick fix and they need to stay on them long term, and be prepared for the financial cost.

YANBU: Pharmaceutical companies/pharmacies/ pharmacists etc should tell people they are likely to need to take this for life and pay for it themselves unless it becomes available to all on the NHS.

OP posts:
Backawayfromthesausage · 26/04/2026 08:17

doglover90 · 26/04/2026 07:49

A lot of obese people start off overweight. Surely preventative weight loss injections would be a good idea?

Please don't be passive aggressive towards me, it's nasty and uncalled for. I'm genuinely curious.

A couple of main stream pharmacies now prescribe at bmi 25.

RoseField1 · 26/04/2026 08:07

doglover90 · 26/04/2026 07:49

A lot of obese people start off overweight. Surely preventative weight loss injections would be a good idea?

Please don't be passive aggressive towards me, it's nasty and uncalled for. I'm genuinely curious.

The drugs are licenced for what they are licenced for. Off label use is becoming more common and FWIW I do agree with you that they are probably beneficial overall to people who aren't obese but are overweight. But what is a good idea and what is licenced aren't always the same thing.

doglover90 · 26/04/2026 07:49

RoseField1 · 26/04/2026 04:00

Amazing that you've read this thread and still need to ask that question! Obesity is a disease and it continues to affect people even after losing weight. That's why it's considered an acceptable risk to continue taking WLI once fat is lost because the likelihood of regaining weight is very high. Whereas a person who is just a bit overweight doesn't have that likelihood of becoming obese so the risk of introducing a drug with potential side effects just to lose a bit of weight isn't considered acceptable.
In fact there are clinics prescribing off label to people who aren't obese and I'm sure that's the direction of travel but it's not that difficult to find the answer to your question if you give it a bit of thought.

A lot of obese people start off overweight. Surely preventative weight loss injections would be a good idea?

Please don't be passive aggressive towards me, it's nasty and uncalled for. I'm genuinely curious.

Backawayfromthesausage · 26/04/2026 07:02

i fully intend to stay on long term. I want all the benefits the drugs bring, from reduced cancers on, and I don’t want to live my life struggling with my weight, been maintaining on it at a bmi 20 for about 14 months or so now, weight very stable and feel better than I have in a long time.

and that’s a choice I’m making, others will chose to come off, and maintain without, this is an equally valid choice and is no different to when you stop any other diet and they will succeed. Others will come off and find they do start to regain, and they can just buy another pen, as long as it’s within a year of stopping, and they don’t need to become overweight again, they can say go from bmi 20 to 22 and buy one. And just bring their weight back to where they wish, then start on their own again, thus only needing a pen sporadically. This is also a valid choice.

and that’s what we have op. Choices. Our bodies. Our money, our choice.

Jellybelly80 · 26/04/2026 05:03

WellConfusedandDazed · 25/04/2026 21:56

‘fat people eat too much healthy food’ 😂 yeah that’s what they say, now don’t eat so much brocoli, or you’ll get fat.

I was willing to give you the benefit of the doubt whilst deciding not to reply to the aggressive reply you had but your comment about broccoli has let you down

Fact - if a person could physically eat 3500 calories worth of broccoli a day and weren’t in a calorie deficit at the end of the day they would gain weight.

Eating healthy foods, Im with you on this. I was the same. I ate clean. Very clean. Everything was home made - I have someone who cooks for me. In fact I’d go as far as to say that my diet was my MO and I could cope with obesity to a certain extent by telling myself - I’m not a fatty who scoffs crisps and burgers and all manners of other rubbish. But my portion sizes were way off and I’d usually have another late night meal or eat other very healthy food in secret. I don’t know how much I was eating calorie wise but I wasn’t in a calorie deficit so I gained weight. Yet as soon as I started eating 1400/1500 calories a day so that I’d be in a calorie deficit of 400/500 daily I lost weight with the help of Mounjaro. Thirty kgs at no more than 450 gms a week for as long as it took.

Your nutritionist - I think it’s great you saw one. I’ve not had a nutritionist on this journey with me but I have and still have counselling to deal with what made me feed my emotions in the first place.

Oh and I was a crossfitter for years before I started Mounjaro so I was very fit but I was still on medication for high BP and prediabetes. My cholesterol had also started to go wrong. Now though I’m off all meds and my cholesterol is perfect. I don’t do CrossFit anymore but I do have functional fitness type personal training twice a week, and I also do two home based session online that my PT sets up for me to do alone on other days.

I call it my ‘whole person approach to me’ and it covers good emotional, mental and physical health as being key to everything I need at 68 to hopefully get another good few decades of life out of me.

eta - it’s never crossed my mind to be on Mounjaro lifelong and I’ll do whatever I can not to be.

RoseField1 · 26/04/2026 04:00

doglover90 · 26/04/2026 02:54

If people can take maintenance doses of weight loss injections once they're at a healthy weight, why can't slightly overweight people access them? It seems unfair that you have to be very overweight to be able to get these when they clearly have a massive impact.

Amazing that you've read this thread and still need to ask that question! Obesity is a disease and it continues to affect people even after losing weight. That's why it's considered an acceptable risk to continue taking WLI once fat is lost because the likelihood of regaining weight is very high. Whereas a person who is just a bit overweight doesn't have that likelihood of becoming obese so the risk of introducing a drug with potential side effects just to lose a bit of weight isn't considered acceptable.
In fact there are clinics prescribing off label to people who aren't obese and I'm sure that's the direction of travel but it's not that difficult to find the answer to your question if you give it a bit of thought.

doglover90 · 26/04/2026 02:54

If people can take maintenance doses of weight loss injections once they're at a healthy weight, why can't slightly overweight people access them? It seems unfair that you have to be very overweight to be able to get these when they clearly have a massive impact.

montysmaw · 26/04/2026 02:43

weighmoreweighless · 25/04/2026 11:45

At first there was lots of talk about WLI injections helping to reset relationships with food as you lost weight so that accompanied by lifestyle adjustments, when it came to stopping, you should be able to maintain your weight.
There are many threads now and back at the beginning on the board where people are saying they only intend to take it for a short time. Also posters dismayed to find they’ve regained the weight. Plenty of posters using WLI as a “kickstart” or saying they can afford it for a certain amount of time only. Reading the board it’s obvious that lots of posters don’t know that this is very likely to be a long term, if not life long medication. Or perhaps it’s just denial and they do actually know but think they’ll take their chances and hope it doesn’t turn out that way.

Of course when you stop taking an apatite suppressing drug then your apetite will stop being suppressed.

You will then probably eat more and most likely gain weight. If you stop reducing calorues after ANY diet you will regain weight. Ts not complicated.

If people were able to resist hunger and eating cues on their own they wouldnt fat and there would be no market for the drugs.

I know that without @LI, hunger and cravings will beat me. I will stay on them so long as I have a penny in the bank and breath in my lungs. That was always my intention. I was not misled. They have changed my life imeasurably for the better.

bridgetreilly · 26/04/2026 02:42

I get Mounjaro on the NHS because it is the only drug which successfully controls my diabetes. And my diabetes specialist has been clear that I can expect to be on it for as long as it is still doing so.

FruitFlyPie · 26/04/2026 02:32

Yabu, it's well known that no weight loss method is a once off, then works for life. Even gastric bypass surgery isn't a guarantee of being thin for life, and people often put weight back on.

mumofoneAloneandwell · 26/04/2026 02:21

Agree that they should be labelled as lifelong

CrazyGoatLady · 26/04/2026 02:15

I can only really speak from my own experience @weighmoreweighless and I think my answer would have to be "it's complicated and it's different for everyone".

I used Mounjaro for 12 months. I had just tipped over into obese category and was borderline Type 2. Lost 3 stone. MJ reduced the food cravings and allowed me to change my diet, establish an exercise regime, etc.

Maintained my lower weight successfully for 6 months without WLI with that fairly strict food and exercise regime in place. Low GI/moderate carb diet. Restricted alcohol to 1-2 days a week. Minimal UPF, sweets, chocolate, etc. Cooking from scratch. Gym 3-5x per week, 2 of those sessions strength training, plus dog walking and animal care duties, a bit of cycling with DS2.

While I could make my health a main priority, it was fine. Then we had a family crisis and I was pulled in loads of different directions. My stress levels increased. Wasn't sleeping. Having to be away from home a lot due to caring responsibilities for elderly relative who doesn't live close by. More convenience food. Work stress increased too, there are likely redundancies coming (though not my role, my department will be affected) and we are short on the on call rota due to sickness and clinical leads/managers leaving and not being replaced, so I'm having a lot of nights of broken sleep at the moment (hence being wide awake at 2am!). That increases my food/sugar cravings because I'm tired in the day. Less energy for exercise. Poor immunity, I've caught every bug going this year so my training has been inconsistent.

Surprise, surprise - prediabetes returned and with it the food noise, weight began to creep up. I went back on a low dose of MJ to try to control it and it's helped with ensuring it doesn't get worse, but the only thing that will actually fix it and help me actually BE healthy as opposed to just being in a theoretically healthy BMI category is being able to prioritise my health in the way I did when I was maintaining without it.

I now view MJ as not a weight loss medication, but a medication that treats the underlying metabolic disease that causes the obesity. However, it doesn't fix the lifestyle based causes of said metabolic disease. There's also a genetic link in my family, so in my case it's genes + lifestyle factors - I'm predisposed to developing Type 2 already.

If you've been obese/overweight and particularly had associated metabolic disease, then staying a healthy weight absolutely is a lifetime project, no doubt about it. WLI may well have to be part of that for some people. IME it's possible to do it without WLI, but it's hard when the odds are stacked against you in other ways.

3flyingducksarrive · 26/04/2026 01:49

Strangerthanfictions · 25/04/2026 22:14

Isn't there emerging thought that once you keep the weight off for a certain amount of time (granted long, like years) your body will eventually surrender to that being your new normal and it will be much easier to maintain with decent habits, like a metabolism correction or lowering your bounce back ceiling? Maybe it's a bit early to tell still with the drugs but I know it's been said about any weight loss method that if you battle tooth and nail to keep it off you eventually hit a point where it becomes easier as your body has accepted this is its new default size give or take and will not want to bounce back as readily to the old heavier weight, although of course terrible habits and overeating will override that but it's not the same as when we lose weight and the body is actively wanting to regain it

That was the theory back when I started on the meds. Thinking has now changed.

If you want to know more about the science, Dr David Kessler's book Diet, Drugs and Dopamine is fascinating. He's the former head of the CDC and uses ozempic himself. Some people can come off ozempic and keep the weight off but most can't and it's not due to will power.

Binus · 25/04/2026 22:16

Jellybelly80 · 25/04/2026 21:10

@SilenceInside Everyone hopes they'll be in the few that manage to maintain weight lost without medication, in the same way that everyone hopes they'll be in the few that maintain the weight lost when they use dieting approaches alone

Hi there, I disagree that everyone hopes they’ll be in the few that manage to maintain weight lost without medication. In fact I’d go as far as to say that more and more people on the weight loss boards are looking at using it life long. I’m not and as a result it can be a nice surprise to find others on the boards who are of the same frame of mind.

Mmm, I rather hope I wouldn't be one of the people who kept the weight off without the jabs. Because I've been paying for my maintenance dose a few months now, and have every intention of staying on them. So if I magically found out I was one of the people who didn't need to do that I'd have wasted my money!

toothcrackedow · 25/04/2026 22:16

I think they’re now being accepted as lifelong medications.

I think that if you go to your GP with proof of having been on them and proof of responding well, you should get them prescribed to you on the NHS.

Strangerthanfictions · 25/04/2026 22:14

3flyingducksarrive · 25/04/2026 10:56

The two year guideline was in the NICE document. I think it's become much clearer over the last few years that there is more to obesity than eating habits and exercise habits. It seems that we need to think of obesity as a chronic disease--the evidence is there that diets don't work in the long run and GLP1 drugs are no different.

I've been on ozempic for nearly 4 years. My GP said she was telling her patients to expect to be on the medication for 2 years and then review. She's really clear now that it is a lifelong medication for most people. If you can shift your weight and keep it off after titrating off the med, you're an outlier. Most of us cannot.

I think you are being very unreasonable to say that people should have to fund the medication themselves. Effectively treated obesity will save the state a lot of money in the long run. I think the meds will be more accessible as they come off patent. The pill form of semaglutide seems very interesting and should be cheaper as there's no patented needle system

Edited

Isn't there emerging thought that once you keep the weight off for a certain amount of time (granted long, like years) your body will eventually surrender to that being your new normal and it will be much easier to maintain with decent habits, like a metabolism correction or lowering your bounce back ceiling? Maybe it's a bit early to tell still with the drugs but I know it's been said about any weight loss method that if you battle tooth and nail to keep it off you eventually hit a point where it becomes easier as your body has accepted this is its new default size give or take and will not want to bounce back as readily to the old heavier weight, although of course terrible habits and overeating will override that but it's not the same as when we lose weight and the body is actively wanting to regain it

DoAWheelie · 25/04/2026 22:04

Research has shown that our bodies try to regain weight and get back to our previous size, but that it's "memory" is around two years. So if you maintain target weight for over 2 years it's much easier to maintain from there.

WLI should probably be used for 2-3 years after target weight is achieved and then slowly tapered off. If people start to regain then ramp back up and try again in another 6-12 months.

SilenceInside · 25/04/2026 21:59

Well I am sure that some people might need telling if they struggle with understanding food labels and nutrition.

You’ve missed my point, which is that people don’t need dieticians to tell them what is wrong with their diet and how to improve it. If dietician advice was effective at treating obesity and managing maintenance after weight loss then there would be no need for medication. It’s great that a dietician helped you, it’s not something that is proven to be effective for the majority.

WellConfusedandDazed · 25/04/2026 21:56

Backawayfromthesausage · 25/04/2026 21:53

I know it wasn’t your meaning, hence why I said you didn’t think it through before posting.

and no, many fat people just eat too much of healthy food and yes many fat people recognise a healthy portion, the drugs control the hunger. And yes many fat people know how to eat a healthy diet.

it was you who said you agreed with the op, and that people would have to stay in for life, I was pointing out most people on them do over haul their diet.

good luck with the maintenance.

‘fat people eat too much healthy food’ 😂 yeah that’s what they say, now don’t eat so much brocoli, or you’ll get fat.

Backawayfromthesausage · 25/04/2026 21:53

WellConfusedandDazed · 25/04/2026 21:49

Omg could you be more pretentious and condescending ? Yes there are some obese people who have health conditions that have contributed to their obesity. But if you are obese, you are not eating properly. Whether it’s unhealthy food or just too much. You don’t get obese with a ‘healthy’ diet, whatever that is. I didn’t sit around eating chocolate and crisps either. That wasn’t my meaning.

I know it wasn’t your meaning, hence why I said you didn’t think it through before posting.

and no, many fat people just eat too much of healthy food and yes many fat people recognise a healthy portion, the drugs control the hunger. And yes many fat people know how to eat a healthy diet.

it was you who said you agreed with the op, and that people would have to stay in for life, I was pointing out most people on them do over haul their diet.

good luck with the maintenance.

WellConfusedandDazed · 25/04/2026 21:53

SilenceInside · 25/04/2026 21:50

@WellConfusedandDazed "MJ gave me the space and time to change my habits because I didn’t feel hungry." - I think this is the case for many people on Mounjaro, and not all of them will need the services of a dietician to help them understand how to overhaul their diet. For me, I know that I ate portions that were far too large, and then also added on top of meals, extra snacks or treat foods that I absolutely knew I didn't need and weren't healthy or nutritious. I don't need a dietician to tell me that eating a whole tub of Ben & Jerry's of an evening was a poor diet choice!

Edited

You have totally missed my point. Is that what you think dieticians do? Tell people not to eat ice cream? eye roll

SilenceInside · 25/04/2026 21:50

@WellConfusedandDazed "MJ gave me the space and time to change my habits because I didn’t feel hungry." - I think this is the case for many people on Mounjaro, and not all of them will need the services of a dietician to help them understand how to overhaul their diet. For me, I know that I ate portions that were far too large, and then also added on top of meals, extra snacks or treat foods that I absolutely knew I didn't need and weren't healthy or nutritious. I don't need a dietician to tell me that eating a whole tub of Ben & Jerry's of an evening was a poor diet choice!

WellConfusedandDazed · 25/04/2026 21:49

Backawayfromthesausage · 25/04/2026 21:45

hmm, not sure you thought that through before posting it,

firstly and importantly not all fat people eat unhealthy, they don’t all need a diet over haul, its portion size that’s the issue, constant hunger etc.

secondly the drugs force you to overhaul if you need it, because too much fat or sugar and you will have gastro issues,

thirdly, most fat people know exactly how to eat.

im glad you got the help you need to over come your poor diet. Don’t assume everyone is like you, had a shit diet and doesn’t know enough so needs help. Glad you got it though, it’s available in the uk to anyone who wants it too.

Omg could you be more pretentious and condescending ? Yes there are some obese people who have health conditions that have contributed to their obesity. But if you are obese, you are not eating properly. Whether it’s unhealthy food or just too much. You don’t get obese with a ‘healthy’ diet, whatever that is. I didn’t sit around eating chocolate and crisps either. That wasn’t my meaning.

Backawayfromthesausage · 25/04/2026 21:45

WellConfusedandDazed · 25/04/2026 21:38

Don’t live in the UK but I was only prescribed MJ if I agreed to see a dietitian/nutritionist. Slowly she has helped me overhaul my diet. Stopped taking MJ and haven’t regained any weight. I still had a bit more to lose tbh, but am ok with how I look and feel now and I just didn’t feel like taking it anymore. So basically I agree with you. I think unless people change their habits they will just be on the drugs for the test of their life. I honestly think MJ gave me the space and time to
change my habits because I didn’t feel
hungry. That’s the problem (well for me it was). Initially I don’t think I could have coped with the changes as it felt too difficult and overwhelming. MJ can help with this.

hmm, not sure you thought that through before posting it,

firstly and importantly not all fat people eat unhealthy, they don’t all need a diet over haul, its portion size that’s the issue, constant hunger etc.

secondly the drugs force you to overhaul if you need it, because too much fat or sugar and you will have gastro issues,

thirdly, most fat people know exactly how to eat.

im glad you got the help you need to over come your poor diet. Don’t assume everyone is like you, had a shit diet and doesn’t know enough so needs help. Glad you got it though, it’s available in the uk to anyone who wants it too.

WellConfusedandDazed · 25/04/2026 21:38

Don’t live in the UK but I was only prescribed MJ if I agreed to see a dietitian/nutritionist. Slowly she has helped me overhaul my diet. Stopped taking MJ and haven’t regained any weight. I still had a bit more to lose tbh, but am ok with how I look and feel now and I just didn’t feel like taking it anymore. So basically I agree with you. I think unless people change their habits they will just be on the drugs for the test of their life. I honestly think MJ gave me the space and time to
change my habits because I didn’t feel
hungry. That’s the problem (well for me it was). Initially I don’t think I could have coped with the changes as it felt too difficult and overwhelming. MJ can help with this.