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Weight loss injections should be advertised as lifelong medications

108 replies

weighmoreweighless · 25/04/2026 10:39

When Ozempic first came out, the guidelines were for usage to be for up to 2 years. I can’t remember if I read the rationale for that but seem to recall it was in the guidelines.
Thinking back it was along the lines of Ozempic was to be used alongside lifestyle and psychological support to address unhealthy eating habits and psychological drivers for overeating. By the end of two years people were expected to be able to maintain these new habits and weight. Happy to be corrected there but that’s meet I remember reading.

Now we have Mounjaro and many users are saying it’s a lifelong medication similar to blood pressure medication or asthma medication.

From reading the weight loss injections topic there are lots of posters who believe they will take the drug for a few months and that will be it, cured of obesity.

Now many of those who have successfully lost several stones are saying that they will remain on these drugs for life because of course they stop working once you stop, just like any other medication.

There are plenty of threads from posters who have regained weight after stopping. A few posters say they have maintained their weight loss but these seem rare on mumsnet at least.

I know diets don’t work and wish that word would disappear beyond being used to describe what we eat eg vegetarian diet, Mediterranean diet etc. I’d love to see diet replaced with another word or phrase such as healthier lifestyle or similar.

The reason diets fail, or one of them, is that so many people drastically cut their food intake for a few weeks, struggle with hunger, lose a little weight and give up because it’s too hard to sustain that low level of calories, food and nutrients.

The focus should always be on eating a healthier diet, achieving a healthier lifestyle by including more exercise within your own capabilities, less alcohol, not smoking, plenty of vitamin D, good sleep and relaxation habits. It should be a holistic approach, not just eat less, move more. Eat better and yes, move more but it’s more than that. It’s a mindset of needing to change habits for life. Sure we all have times and events where we eat and drink more or don’t exercise as much for a variety of reasons but what matters is what we do most of the time.

With this in mind I’m thinking that the advertising should be changed to reflect this. Companies need to be more transparent about the medications so that people are fully informed that these drugs are not going to be a quick fix or magic cure like people seem to think or hope. I’d be so angry if I’d paid out thousands to lose weight and then when I stopped it came back on because the prescriber hadn’t been completely open with me. There’s been posters who have stuck to healthier eating and increased exercise but still gained weight after stopping.

There’ll be arguments for fully researching the drugs before taking but how many people have the time or understanding of research to be fully informed? Most will just trust what they read in the press or on social media and the pharmacist prescribing. Critical thinking isn’t applied or rather thinking about what happens after. It’s the instant gratification and not thinking of the long term consequences or the financial implications of having to pay out indefinitely or at least until they become available for all on the NHS. Not unlike that packet of jam doughnuts I really wanted to buy yesterday instead of eating a healthy lunch Confused. Just to clarify I wouldn’t have eaten them all. Two of the five for sure though and maybe a third after the school run. I’m a terrible sugar fiend.

This has ended up all disjointed because I can’t go back up the page to edit as I’m typing. I’ll try once I get to the edit option. I have ADHD and my thought processes are all over the place and I go off on tangents. Sorry.

TL:DR Should pharmaceutical companies/pharmacies/doctors/pharmacists change their advertising and recommendations to say that WLI (weight loss injections/medications) are likely to be needed to be taken for life to control obesity due to the likelihood of weight being regained once stopping even in cases of maintained healthy diet and lifestyle due to the chronic nature of obesity?

I’m going to try and edit this now into some semblance of order but if it remains chaotic I’m sorry. It at least has paragraphs even if it does jump around like a flea at a fair.

Poll:

YABU: No, people who take these drugs should realise that these aren’t a quick fix and they need to stay on them long term, and be prepared for the financial cost.

YANBU: Pharmaceutical companies/pharmacies/ pharmacists etc should tell people they are likely to need to take this for life and pay for it themselves unless it becomes available to all on the NHS.

OP posts:
New posts on this thread. Refresh page
RootsOfTheTree · 26/04/2026 17:18

Ponoka7 · 26/04/2026 16:40

Are you a research consultant? Involved in infectious disease? I'm actually losing weight naturally, just had to get my shit together. But I've excellent genetics, mixed heritage. Looking at the people who I know from across Africa, I do think that activity and healthy, but overeating, does make a difference when it comes to obesity. I know quite a few builders who are obese type 1, they are in better health than semi sedentary bmi normal range men of the same age. As we are all 57- 75, we are seeing a lot of poor health in people who you would think will age well.

No I’m not a “research consultant”. No idea why you ask. And why are you talking about infectious diseases now? It’s well known that bmi based risk profiles don’t take into account very fit, muscular people. As you said you were discussing losing weight with your consultant I assumed you thought you were overweight. Anyway I’ll leave you to your superior genetics. Mine are average so I’m aware I’m at risk of diseases like most other people (not the superior ones, obviously) 🙄

Backawayfromthesausage · 26/04/2026 16:49

Ponoka7 · 26/04/2026 16:43

That article is concerning people who have type 2 diabetes or transcatheter procedures. When you Google 20% comes up, but a large percentage were smokers who stopped. So no decisive studies, yet.

What> google. It’s just completed final trials and about to be approved for cardio vascular disease treatment. Honestly google is a thing you can t rely on social media nd people to research for you. And certainly not me, as I abhor laziness.

Ponoka7 · 26/04/2026 16:43

Backawayfromthesausage · 26/04/2026 15:22

I mean this politely bit firmly. I shall do it this time. But please learn to use google instead of asking people to search for you. There are literally dozens of articles on it,

https://www.healthline.com/health-news/tirzepatide-reduces-risk-major-cardiovascular-events

That article is concerning people who have type 2 diabetes or transcatheter procedures. When you Google 20% comes up, but a large percentage were smokers who stopped. So no decisive studies, yet.

Ponoka7 · 26/04/2026 16:40

RootsOfTheTree · 26/04/2026 14:54

It isn't as clear as obese = worse health outcomes.

It really is. You seem to feel you have been somehow cleared as not at the cardiovascular and cancer risks of obesity @Ponoka7. That cannot be the case. You may well be healthy now (and I hope you are and remain so) but your current status does not exempt you from the future risks of obesity.

Are you a research consultant? Involved in infectious disease? I'm actually losing weight naturally, just had to get my shit together. But I've excellent genetics, mixed heritage. Looking at the people who I know from across Africa, I do think that activity and healthy, but overeating, does make a difference when it comes to obesity. I know quite a few builders who are obese type 1, they are in better health than semi sedentary bmi normal range men of the same age. As we are all 57- 75, we are seeing a lot of poor health in people who you would think will age well.

Backawayfromthesausage · 26/04/2026 15:23

Ponoka7 · 26/04/2026 11:38

I was offered a heart scan as part of research for over 55's. Although I'm obese, my heart is healthy and my cancer risk low. It isn't as clear as obese = worse health outcomes. He is a research cardiovascular consultant, at the time he was working out of Liverpool Royal hospital. All you mention is true, but with just Statins and a lifestyle that we are supposed to follow, will do the same. He felt there are risks to lifelong medication and we shouldn't be medicating at the lower end of obesity. He likened it to medicating lung conditions in heavy smokers. You are just putting off the inevitable early death, unless the addiction is given up.

This doesn’t make any logical sense, in fact it’s highly contradictory, are you saying yoh will go on life long statins? But not weight loss injections which negates the need for them, and you were told you don’t have risks by being obese? What is a research consultant exactly?

Backawayfromthesausage · 26/04/2026 15:22

Ponoka7 · 26/04/2026 11:42

Have you got a link to that? I mentioned this, my heart is healthy so it doesn't apply to me, but he said the research isn't that clear and it's around 20%, but for some categories and a by-effect of WLI was many people stopped smoking.

I mean this politely bit firmly. I shall do it this time. But please learn to use google instead of asking people to search for you. There are literally dozens of articles on it,

https://www.healthline.com/health-news/tirzepatide-reduces-risk-major-cardiovascular-events

Mounjaro, Zepbound Lowers Risk of Cardiovascular Death by 62%

GLP-1 weight loss drugs containing tirzepatide (Mounjaro, Zepbound) can reduce heart-related health risks for people with serious heart conditions, according to new research.

https://www.healthline.com/health-news/tirzepatide-reduces-risk-major-cardiovascular-events

RootsOfTheTree · 26/04/2026 14:54

It isn't as clear as obese = worse health outcomes.

It really is. You seem to feel you have been somehow cleared as not at the cardiovascular and cancer risks of obesity @Ponoka7. That cannot be the case. You may well be healthy now (and I hope you are and remain so) but your current status does not exempt you from the future risks of obesity.

HereIGoOnceMore · 26/04/2026 11:52

Hmm. That’s scary advice. Just because someone’s heart is physiologically OK doesn’t mean they are not at risk from obesity related inflammatory events.

I’d be curious to learn what product this cardiologist is being paid to research.

Ponoka7 · 26/04/2026 11:44

RootsOfTheTree · 26/04/2026 09:03

20% reduction in heart attacks. Obviously obesity is a major risk for heart disease too. I’m not sure what your consultant is reading. The NHS is starting to prescribe wegovy for heart disease prevention.

I started on 2.5mg and am continuing on that. I’ve lost 5 stone so far and would like to lose another 1/2 stone.

https://www.ucl.ac.uk/news/2025/oct/weight-loss-drug-helps-heart-regardless-amount-weight-lost

Edited

He isn't reading anything, he's part of the research. As my pp said, WLI do stop other addictions, such as smoking and paying for WLI spurs people on to exercise. Interestingly so did paying for other forms of weight loss, even slimming world.

Ponoka7 · 26/04/2026 11:42

Backawayfromthesausage · 26/04/2026 09:00

Yes I’m surprised too, it’s over 60 percent reduction in heart events I think, likely just anothee doctor who hasn’t bothered to educate himself.

Have you got a link to that? I mentioned this, my heart is healthy so it doesn't apply to me, but he said the research isn't that clear and it's around 20%, but for some categories and a by-effect of WLI was many people stopped smoking.

toothcrackedow · 26/04/2026 11:40

Ponoka7 · 26/04/2026 11:38

I was offered a heart scan as part of research for over 55's. Although I'm obese, my heart is healthy and my cancer risk low. It isn't as clear as obese = worse health outcomes. He is a research cardiovascular consultant, at the time he was working out of Liverpool Royal hospital. All you mention is true, but with just Statins and a lifestyle that we are supposed to follow, will do the same. He felt there are risks to lifelong medication and we shouldn't be medicating at the lower end of obesity. He likened it to medicating lung conditions in heavy smokers. You are just putting off the inevitable early death, unless the addiction is given up.

I think it’s quite widely accepted that obesity = worse health outcomes. I’d be looking for a new consultant!

Ponoka7 · 26/04/2026 11:38

toothcrackedow · 26/04/2026 08:52

I’m curious as to why a consultant discouraged medication with huge cardiovascular benefits?

I was offered a heart scan as part of research for over 55's. Although I'm obese, my heart is healthy and my cancer risk low. It isn't as clear as obese = worse health outcomes. He is a research cardiovascular consultant, at the time he was working out of Liverpool Royal hospital. All you mention is true, but with just Statins and a lifestyle that we are supposed to follow, will do the same. He felt there are risks to lifelong medication and we shouldn't be medicating at the lower end of obesity. He likened it to medicating lung conditions in heavy smokers. You are just putting off the inevitable early death, unless the addiction is given up.

Backawayfromthesausage · 26/04/2026 09:52

toothcrackedow · 26/04/2026 09:06

I know my dad’s cardiologist said he was recommended them (as a cardiologist!!!) but he decided not to because there were reports of temporary worsening of diabetic retinopathy. Seems you can be a doctor and still be a bit silly!

I think the medical community has really shown a shameful under belly with these medicines. So many anecdotes now coming out about doctors giving misinformation and personal bias. Of course there are many who are also knowledgeable and work in the patients benefits, my gp was one, she recommended them even thou she couldn’t prescribe. And they all go through training on them at that surgery. As they feel they are responsible for the overall health of their patients, and should be in a position of knowledge.

however it’s now become apparent, many doctors don’t know anything about them, make erroneous assumptions, give bad or dangerous advice, use their personal biases to discuss them ie your fat so eat less and move more, and won’t help their patients unless they are paid more and see the cash.

up until now there was a misconception that Doctors were knowledgeable. Worked in the patients best interests, and wouldn’t give misinformation, they’d decline to comment or read up first. And we have now all realised it’s far from the truth, and I suspect this is because it is fat people they are dealing with.

Blogswife · 26/04/2026 09:23

I agree that people should understand that it’s a lifelong drug Unfortunately many people are using the drug as a quick fix , not exercising & not learning how to eat healthily ( my own experience of the dozen or so people that I know who are using it
) .
Of course there will also be those that are doing it properly but I imagine they’ll also be relying on it for a long time . Either way the NHS need to build life long dependency into their calculations when budgeting for its use with patients and pharmaceuticals need to ensure the costs involved in lifetime use are communicated to users when starting out

Clefable · 26/04/2026 09:06

I think it’s a tricky one as obesity is so multi-faceted. Some people have struggled with being overweight/obese their entire life and have never really been a healthy weight, I think for those people then WLIs are probably a long-term or lifelong mediation. But for others, weight gain has been something situational, related to other health issues, a result of an emotional trauma, and for those people then maintaining without may be possible.

I wasn’t obese till after I had kids, I found it very hard to lose the weight during lockdowns and after and my mum had stage 4 cancer (and subsequently died from it) so I wasn’t mentally in a great place. When I had my maintenance talk with my provider, we discussed my weight history and that I had spent 30 years at a healthy weight previously, and decided that being off WLIs was probably possible for me. It has proved to be the case, I’m a year in and still 7lbs down on what my weight was when I stopped them.

So I think advice needs to be more tailored, really.

toothcrackedow · 26/04/2026 09:06

Backawayfromthesausage · 26/04/2026 09:00

Yes I’m surprised too, it’s over 60 percent reduction in heart events I think, likely just anothee doctor who hasn’t bothered to educate himself.

I know my dad’s cardiologist said he was recommended them (as a cardiologist!!!) but he decided not to because there were reports of temporary worsening of diabetic retinopathy. Seems you can be a doctor and still be a bit silly!

RootsOfTheTree · 26/04/2026 09:03

Ponoka7 · 26/04/2026 08:28

What are the benefits? I had an appointment with a cardiovascular consultant and he was generally against them. He talked me out of trying them. I am worried about gaining even more, once stopped. How much is your maintenance dose?

20% reduction in heart attacks. Obviously obesity is a major risk for heart disease too. I’m not sure what your consultant is reading. The NHS is starting to prescribe wegovy for heart disease prevention.

I started on 2.5mg and am continuing on that. I’ve lost 5 stone so far and would like to lose another 1/2 stone.

https://www.ucl.ac.uk/news/2025/oct/weight-loss-drug-helps-heart-regardless-amount-weight-lost

Backawayfromthesausage · 26/04/2026 09:00

toothcrackedow · 26/04/2026 08:52

I’m curious as to why a consultant discouraged medication with huge cardiovascular benefits?

Yes I’m surprised too, it’s over 60 percent reduction in heart events I think, likely just anothee doctor who hasn’t bothered to educate himself.

toothcrackedow · 26/04/2026 08:52

Ponoka7 · 26/04/2026 08:28

What are the benefits? I had an appointment with a cardiovascular consultant and he was generally against them. He talked me out of trying them. I am worried about gaining even more, once stopped. How much is your maintenance dose?

I’m curious as to why a consultant discouraged medication with huge cardiovascular benefits?

Backawayfromthesausage · 26/04/2026 08:49

Ponoka7 · 26/04/2026 08:28

What are the benefits? I had an appointment with a cardiovascular consultant and he was generally against them. He talked me out of trying them. I am worried about gaining even more, once stopped. How much is your maintenance dose?

Wow, they are about to be approved for treating cardio vascular disease. You got some bad advice there,

you can google. But so far cardio vascular, kidney, liver health improvement, and reduced cancers.

they also think reduced dementia, now in testing.

anti ageing also in testing, as they have found the anti inflammatory effect allows our cells to regenerate, (internal organs) as ageing is effectively inflammation, whenever we get ill through our lifetimes, be it a cold or a virus, or a cut or bruise etc, as much as we recover, our cells always carry a marker of that, that’s ageing, and by reducing the inflammation the cells are able to regenerate, and they have seen ageing being reversed, stopped or slowed, so now testing is being done on this, so they can know definitively.

Focalpoint · 26/04/2026 08:46

First thing my doctor (specialist obesity GP, not in the UK) said to me when we spoke about GLP1 was that I had to be prepared to take them for life, in the same way as most medications for chronic diseases are life long (blood pressure tablets etc). GLPs aren’t funded by government where I live but they are prescribed by GP in the same way as other drugs.

Difference from what I know of the Uk is because they aren’t funded by the NHS, the NHS GPs don’t prescribe them, offer advice and follow up etc so now the culture sees them as lifestyle related rather than a chronic disease medication.

We have years of diet culture/ weight stigma causing people living with the disease of obesity to feel shame and we live in a culture where we are subject to harsh judgement for having obesity. Now thankfully science has proved the causes are multi faceted and there are medical treatments that treat the metabolic causes of the disease. These treatments are very expensive and are being dropped into the diet culture society that is evolving.

Ultimately when they come off patent and are cheaper it will all normalise.

I voted YABU because all this information about GLPs exists, nothing is “advertised” it is prescription medication, online prescribers are filling the vacuum caused by lack of NHS funding. And my guess would be that vast majority of people taking are informed and trying to improve their long term heath.

Ponoka7 · 26/04/2026 08:28

RootsOfTheTree · 25/04/2026 16:03

Just to add, I happy to carry on taking them for life just for the cardiovascular benefits, whether I need them to maintain my weight or not.

What are the benefits? I had an appointment with a cardiovascular consultant and he was generally against them. He talked me out of trying them. I am worried about gaining even more, once stopped. How much is your maintenance dose?

Backawayfromthesausage · 26/04/2026 08:27

Sartre · 26/04/2026 08:22

I’d be interested in the long term effects of these drugs. They’re so fresh and we don’t know enough about them yet. I’d hazard a guess people will absolutely need them long term to prevent weight gain. Not everyone but I think it’ll work the same as people who need antidepressants long term.

My mum is one of these people. Antidepressants I think her whole adult life and whenever she’s tried to stop, she gets so depressed she has to go straight back on them. She’s been taking WLI for around a year and has got very slim but is still taking them so she doesn’t regain. She wasn’t obese when she started but was about 3 stone overweight so almost. I know what she’s like, she won’t stop now and will use them forever.

I don’t really get why people use the royal “we” in sentences like this when what they mean is they don’t know. Glp’s have been in use for over 20 years, in trials for 15 years before it. They have nearly 40 years data, they know. The health authorities know. And yes they can extrapolate from the diabetes patients data on how the human body reacts to the drugs.

Sartre · 26/04/2026 08:22

I’d be interested in the long term effects of these drugs. They’re so fresh and we don’t know enough about them yet. I’d hazard a guess people will absolutely need them long term to prevent weight gain. Not everyone but I think it’ll work the same as people who need antidepressants long term.

My mum is one of these people. Antidepressants I think her whole adult life and whenever she’s tried to stop, she gets so depressed she has to go straight back on them. She’s been taking WLI for around a year and has got very slim but is still taking them so she doesn’t regain. She wasn’t obese when she started but was about 3 stone overweight so almost. I know what she’s like, she won’t stop now and will use them forever.