No - I haven't used it but have seen a few sites made with it. It depends what you wan thte site for and how professional it needs to look. From my admittedly scanty knowledge of 'build it yourself' products, it looks like Mr Site is the best; any cheaper and it will be difficult and might not look like you want.
If you can afford someone to do it for you, even better, but that starts at a few hundred pounds. And if you can afford graphic design, etc, even better but that's more!
Actually, if you have time, try Dreamweaver. Do the tutorial and see how it goes! You would need to register a domain name and get hosting separately though.