Blimey, 3 nights away a week! Not surprised you're fed up Galaxy. It sounds like you and dh both want a change - I'd go for it, e.g.
Maybe don't resign for this last 2 weeks before dh starts his new job, if he is well enough to give you support, and do maximum you can to find the job you want - writing to local companies you would like to work for? meeting with people there? any more agencies you can get in touch with? Ring the people who offered you an interview, find out what's going on?
Have you worked out what the absolute minimum money you can sustain your current lives on would be? only you know how long you could keep going if you didn't find a job straight away. there is a risk in resigning without something to go to so how big a risk is it?
all this is so obvious - sorry if offensively so! best wishes