What hatwoman said.
Before committing to anything (including voluntary) check it out with your partner to see what their true views on it is, and how you would divide the labour between you both at time when you're both at home. Getting this sorted could save your relationships all round, and if you feel totally supported by your partner (if you've got one) then it will automatically boost confidence right from the point when it's just an idea. If you get rubbish commitment from them, it hasn't really been thought through by them, and you could end up doing it all. How many threads have we read on MN about this??! Avoid that scenario if poss.
Have a chat to other parents and see if there are others around who are thinking about it. Any support there?
Research childcare in your area and go and check them all out with a weather eye, now while you've got the time and non-pressurised judgement. If you're worrying about it later, it will just make things harder. The wrong childcare is just horrible!! Have more than 1 option up your sleeve.
Set up internet shopping for food and get that going a week or two before you go back! It takes time to get into that routine.
CVs - it looks better if you've done something voluntarily if there's a big time gap. It shows personal commitment, especially if it's doing something different to before. It may also provide a recent reference, which would be a big boost for a job application.
Keep the CV clear and relevant, with your details very easy to find! Remember it won't be the only one on the HR manager's desk. If you're applying for a variety of jobs, you could have several different ones that match your relevant experience and skills to the criteria on the job spec. Think of things from the employer's perspective.
Get a few people to look at what you're going to send in - it's easy to miss spelling/grammar errors when it's your own work, especially if you only wrote it last night.
Don't take it personally if it takes a while. When offered an interview, do some homework on the job and the company. Have some questions ready.. one good one is 'what would you have me doing during my first week at the job?' Helps them visualise you doing it..
Sort out your clothes and some kind of routine where everyone who can contributes.
Get two bottles of wine in, if it's your thing. One to have when you pass the interview, the other to - at least - open after you've done your first day!! It's a whole job in itself just to land a job these days.