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Feminism: Sex and gender discussions

A Question of Science Podcast - how does biological sex affect health?

29 replies

CaveMum · 27/10/2026 21:58

Haven’t had a chance to listen to this yet, but the blurb sounds promising:

“Our biological sex affects every cell in our body, so how does it influence our health - from embryo development through to the risk of disease and diagnosis? How and why do some conditions affect females and males differently? And what can we do to ensure medicine is safe and effective for everyone, after decades of male biology bias?

Across autoimmune disorders, cancer, dementia, heart disease and even responses to everyday medications, sex‑based biological differences can shape who becomes ill, how symptoms appear and what treatments work.

Join our expert panel as they explore sex differences in biology, hormones and gene regulation.

Panel:
Prof Edith Heard, CEO of the Francis Crick Institute
Natasha Karp, Biostatistician at Astra Zeneca
Prof Petter Brodin, Garfield Weston chair of Neonatology and Professor of Paediatric Immunology, Imperial College, London
Caroline Criado Perez, Author of Invisible Women”

https://podcasts.apple.com/gb/podcast/a-question-of-science/id1837162757?i=1000797381222

How does biological sex affect health?

How does biological sex affect health?

Podcast Episode · A Question of Science · 21 October · 46min · Video

https://podcasts.apple.com/gb/podcast/how-does-biological-sex-affect-health/id1837162757?i=1000797381222

OP posts:
Imdunfer · Today 17:20

HelpMeINeedWine · Today 17:14

Will take a look, thanks. He had 5 days of IVIG in May, then had two Rituximab Infusions in July and is due to have them 6 monthly for the next 18-24 months.

Life has changed immensely for both of us so it's taking a lot of getting used to.

Anyway, thanks again and sorry for the derail.

Small comfort, I guess but at least he's on the biologics. I hope they work for him. I hope you have support too, it's tough on the partner when someone has a lifelong illness.

Seagulldancing · Today 17:24

Imdunfer · Today 08:49

MS is 4 times as likely to strike women as men because it's an autoimmune disease. The genes that regulate the immune system are on the X chromosome. Men have only one, women get a double dose.

Women have a stronger immune response than men because of this, and a stronger immune system is more likely to go rogue looking for something to attack.

I have rheumatoid arthritis and a woman is 8 times more likely than a man to have that. I hope you don't have MS?

Thats interesting. My family is rife with autoimmune issues, but oddly only in the men. That second X must be protecting the rest of us.

Imdunfer · Today 17:44

Seagulldancing · Today 17:24

Thats interesting. My family is rife with autoimmune issues, but oddly only in the men. That second X must be protecting the rest of us.

Well they are heritable, so maybe there's something problematic about the X's that your males are inheriting? Genes are very interesting in the way the exact same one can act differently in men and women. The same region of mutation on gene 15 produces either Prader Willi or Angelman's in the child, depending on whether the gene came from the father for the first or the mother for the second

ScrollingLeaves · Today 19:11

BinturongsSmellOfPopcorn · Yesterday 09:37

Ive mot listened yet, but not everything is about trans people. They've got 45 minutes to cover a huge subject, I'd rather they didn't waste it on a tiny proportion of the population - many of whom aren't taking any hormones and so will be the same in their medical responses as any other member of their sex.

The introduction to the podcast is this:

"At the most basic level, sex is determined by our chromosomes. Two Xs for females, and an X and a Y for males. But as we'll hear, sex is broader than that. It refers to a set of biological attributes, including our hormonal levels, gene expression, and internal and external sex organs - all of which have implications for our health. Science has traditionally ignored the complexity of biological sex, with research and clinical trials largely focused on male biology. But we do know that females and males don't have the same susceptibility to disease, and respond differently to treatment."

Why would you refuse to listen to something that acknowledges that 8 times difference in your susceptibility simply because it may not cover a tiny group of other people who are irrelevant to the main argument and for whom there is barely any decent research?

a tiny group of other people who are irrelevant to the main argument

You would think so, so it is difficult to understand why a poster like this, even adorned with a rainbow, needs to be on the wall of a local hospital x ray waiting room regarding pregnancy.

Pregnancy status for X-ray examinations

We are legally obliged to rule out the possibility of pregnancy before we can proceed with certain examinations.

To maintain compliance with the lonising Radiation (Medical Exposure) Regulations 2017, Gender Recognition Act 2004 and the Equality Act 2010, we are obliged to ask ALL patients, aged between 11 and 55 years, who are undergoing X-ray examinations between the bottom of the chest and knees, their sex assigned at birth and determine their potential for pregnancy.

This includes individuals identifying as:

  • Non-binary
  • Transgender
  • Intersex
  • Gender non-conforming
  • Female
  • Male
Including those patients in same sex relationships, where one or both have childbearing capacity.

This information will not be recorded or shared without your consent.

*The Radiology directorate are committed to ensuring patients are free from discrimination regardless of their gender identity or sexual preference.

You would think that as a medical department at least they would not use the term ‘sex assigned at birth’ or suggest ‘male’ or ‘female’ are identities even though they had already listed ‘Transgender’.

A Question of Science Podcast - how does biological sex affect health?
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