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Feminism: Sex and gender discussions

Why the NHS puberty blocker trial is appalling

1000 replies

Soontobe60 · 16/11/2025 14:43

Stella O’Malley from Genspect telling it like it is - that a state endorsed trial of puberty blockers for gender dysphoric children should NOT go ahead.
the NHS are not walking into this nightmare blindly - there are enough experts out there telling them what will happen happen to these children if they’re given these life changing drugs.
https://x.com/genspect/status/1989896741358113127?s=61&t=gKvvk-rWmOlYFGMZN8QVvQ

Genspect (@genspect) on X

In a conversation about the Next Generation, podcast host Elliot Bewick @elliotbewick talks with @stellaomalley3 : “This won't be puberty because their reproductive system won't be awakened, it will be a chemical insurgents into their body…and so they...

https://x.com/genspect/status/1989896741358113127?s=61&t=gKvvk-rWmOlYFGMZN8QVvQ

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ProfessorDameFarriersGirl · 30/11/2025 10:07

I came across this link on another thread but its relevant here. Kings College are not only captured but it seems heavily invested in embedding trans activism and overturning the prohibition on puberty blockers for children. Not exactly an impartial partner in this trial.

https://www.transgendertrend.com/gender-activism-nhs/

Gender activism in the NHS - Transgender Trend

Gender activism continues to influence the NHS, with organisations such as LGBT Foundation continuing to peddle their ideological agenda.

https://www.transgendertrend.com/gender-activism-nhs/

OpheliaWitchoftheWoods · 30/11/2025 10:07

Excellent post.

It sums up a number of observations really that seem to form a common pattern whenever the establishment has the word 'trans' involved. The census comes to mind.

It's incoherent and very poorly designed
It appears to be flailing around without any clear intent or reasoning for the desired end point
The desired end point is extremely questionable
All basic good sense, normal standards and ethics appear to have been abandoned
Advisors and consulting groups involved are somewhat interesting in their impartiality and histories, and represent only one very specific agenda
All legal barriers and normal safeguards have been lowered to let it through.

Slothtoes · 30/11/2025 10:08

Igneococcus · 30/11/2025 07:03

In the Times today.
"She said demand for puberty blockers had started rising when the Gids team — along with paediatricians at University College Hospital London who worked with them — failed to publish the results of a study into the drug that found no benefit."

I honestly don't get it. I would ask myself why are they not publishing their results (or only with great delay), what are they hiding? It wouldn't make me want to repeat the trial.

https://www.thetimes.com/article/cfbd017d-d8a4-4410-a732-0a8a188a09ef?shareToken=20cf1929d5c8c5c78415f0f1a35b48f3

There must be legal consequences to hiding losing, stopping gathering or otherwise burying your trial results otherwise what at the HRA and MHRA actually for? There’s loads of regulations around UK trials. I don’t understand why NHS record-keeping is now being given some ‘too difficult’ label to forensically piece back together, while another few hundred kids lives will get ruined by medication because this is too hard or too expensive or too controversial for the adults to actually sort out. It’s an awful prospect.

ArabellaSaurus · 30/11/2025 10:09

TwoLoonsAndASprout · 30/11/2025 09:58

Ok, so, I’m an ex-academic, have spent a stupid amount of my life designing research studies, and teaching students how to do the same, and evaluating those of other researchers. It is clear that the Pathways trial is the most flabbily designed piece of shit ever. I think we’ve established that.

But! What bothers me most is this: what is the goal? I mean, “make these children happier,” sure, but what does that mean? If it is just “alleviate depression,” well, we have drugs for that - drugs that don’t have the diabolical side effects of puberty blockers. So it can’t be that.

The goal must be “remove their perceived gender incongruence.” But what does that mean? It can only mean somehow bring their mental picture of themselves, and their physical body, into a state of congruence.

Which means one of two things. Either help them to accept their sexed bodies as they are, using tools that address this as a mental health or psychological issue. Or cosmetically alter their body to make it match their mental picture.

Puberty blockers do not help a child accept their sexed body. We know this. The flawed data collection from the Tavistock showed this. They lead in 90% or more of cases to a desperate desire for cross-sex hormones. They prevent the brain development that happens in puberty that would allow for a child to mature and realise that there is nothing wrong with their sexed body.

So, by default, this study is starting from the standpoint that the solution to “gender incongruence” is to permanently cosmetically alter a perfectly healthy child’s body.

The study is biased and broken before you even get to the fact that the design is beyond flawed and won’t give any useful results at all, and will physically harm vulnerable children.

How Cass can look anyone in the eye and say that this study is necessary is beyond me.

Yes.

ArabellaSaurus · 30/11/2025 10:10

rogdmum · 30/11/2025 09:15

I forgot about them!

Someone needs to be looking into them.

They don't have a batshit Helen Webberley fronting them, instead, they are working quietly behind the scenes.

nicepotoftea · 30/11/2025 10:12

TwoLoonsAndASprout · 30/11/2025 09:58

Ok, so, I’m an ex-academic, have spent a stupid amount of my life designing research studies, and teaching students how to do the same, and evaluating those of other researchers. It is clear that the Pathways trial is the most flabbily designed piece of shit ever. I think we’ve established that.

But! What bothers me most is this: what is the goal? I mean, “make these children happier,” sure, but what does that mean? If it is just “alleviate depression,” well, we have drugs for that - drugs that don’t have the diabolical side effects of puberty blockers. So it can’t be that.

The goal must be “remove their perceived gender incongruence.” But what does that mean? It can only mean somehow bring their mental picture of themselves, and their physical body, into a state of congruence.

Which means one of two things. Either help them to accept their sexed bodies as they are, using tools that address this as a mental health or psychological issue. Or cosmetically alter their body to make it match their mental picture.

Puberty blockers do not help a child accept their sexed body. We know this. The flawed data collection from the Tavistock showed this. They lead in 90% or more of cases to a desperate desire for cross-sex hormones. They prevent the brain development that happens in puberty that would allow for a child to mature and realise that there is nothing wrong with their sexed body.

So, by default, this study is starting from the standpoint that the solution to “gender incongruence” is to permanently cosmetically alter a perfectly healthy child’s body.

The study is biased and broken before you even get to the fact that the design is beyond flawed and won’t give any useful results at all, and will physically harm vulnerable children.

How Cass can look anyone in the eye and say that this study is necessary is beyond me.

So, by default, this study is starting from the standpoint that the solution to “gender incongruence” is to permanently cosmetically alter a perfectly healthy child’s body.

And cosmetically alter the body for what reason? Even if you agree with the theory, how does treatment that reduces height and bone strength make a girl resemble a boy?

TwoLoonsAndASprout · 30/11/2025 10:15

ALSO!

Cass says in that Times article:

“We wouldn’t want to be starting from here,” she said about the Pathways trial. “It is very unfortunate that in 2011 they didn’t do a controlled trial because it would have been much easier to conduct at that time when there wasn’t the belief and expectations that we have now.”

Human studies cannot be carried out in a societal vacuum. There is a belief system now, and there are expectations now, the existence of which mean that any trial must take these into account. You can’t just say “it’s unfortunate” and throw your hands up and say “best we can do.” (Not that what they’ve come up with is the best. It’s something like the 6th least bad, if that.)

BeKindWisely · 30/11/2025 10:15

TwoLoonsAndASprout · 30/11/2025 09:58

Ok, so, I’m an ex-academic, have spent a stupid amount of my life designing research studies, and teaching students how to do the same, and evaluating those of other researchers. It is clear that the Pathways trial is the most flabbily designed piece of shit ever. I think we’ve established that.

But! What bothers me most is this: what is the goal? I mean, “make these children happier,” sure, but what does that mean? If it is just “alleviate depression,” well, we have drugs for that - drugs that don’t have the diabolical side effects of puberty blockers. So it can’t be that.

The goal must be “remove their perceived gender incongruence.” But what does that mean? It can only mean somehow bring their mental picture of themselves, and their physical body, into a state of congruence.

Which means one of two things. Either help them to accept their sexed bodies as they are, using tools that address this as a mental health or psychological issue. Or cosmetically alter their body to make it match their mental picture.

Puberty blockers do not help a child accept their sexed body. We know this. The flawed data collection from the Tavistock showed this. They lead in 90% or more of cases to a desperate desire for cross-sex hormones. They prevent the brain development that happens in puberty that would allow for a child to mature and realise that there is nothing wrong with their sexed body.

So, by default, this study is starting from the standpoint that the solution to “gender incongruence” is to permanently cosmetically alter a perfectly healthy child’s body.

The study is biased and broken before you even get to the fact that the design is beyond flawed and won’t give any useful results at all, and will physically harm vulnerable children.

How Cass can look anyone in the eye and say that this study is necessary is beyond me.

Exactly. A

And that's why, I think, Hannah Barnes and Hadley Freeman (?) were not allowed to attend the media briefing.
As these are precisely the points they would have raised.

ArabellaSaurus · 30/11/2025 10:19

DrBlackbird · 30/11/2025 09:56

Two quotes from that article stand out for me:

“They asked a 12-year-old to make a decision an adult would struggle with.

The whole ‘it’s parents giving consent’ to the current proposed PB trial is a weaselly specious tactic. Parents would not consent but for the child saying they are ‘meant to be the opposite sex’. So in effect, it is the child consenting.

Without the slightest idea of what they're doing to their bodies and minds.

And this one.

“My Tavistock worker was saying to me, ‘once you have the testosterone, you’ll be a boy’.

And this highlights how there are far too many uninformed, even ignorant, and biased workers in so-called gender care. There to proselytise and recruit to the gender religion rather serving the needs of vulnerable children.

That they have all this information and yet still plan to go ahead and harm further children with the current proposed trial leaves me speechless. I’m sure there are carefully worded articles in the consent form signing away the right to future legal action.

Healthcare professionals can succumb to the heady mix of virtuous beingkind, messiah complex, and the egotism of believing you’re the smartest person in the room leads to hubris for the patients. So, unfortunately it will only be lawsuits that stops the madness.

Parents would not consent but for the child saying they are ‘meant to be the opposite sex’. So in effect, it is the child consenting.

Some parents will be convinced by their child telling them that they need blockers. Some will be terrified, because of the suicide narrative that has been deliberately and recklessly pushed, over and over, that if they don't do as instructed, they may lose their child, either to estrangement or suicide.

Some parents may have other reasons for wanting to stop the development of their child, and/or wanting a child of the different sex.

In most cases, parents only want the best for their child, of course. But we also cannot ignore the existence of abusive parents. It should also be noted that the statistic about parents and convictions for sexual abuse, from the GIDS patients.

There are also some parents with strong beliefs about, for example, reincarnation, who have 'trans' children, who I would say are unbalanced themselves. Munchhausens by proxy is a thing.

TwoLoonsAndASprout · 30/11/2025 10:23

BeKindWisely · 30/11/2025 10:15

Exactly. A

And that's why, I think, Hannah Barnes and Hadley Freeman (?) were not allowed to attend the media briefing.
As these are precisely the points they would have raised.

Sonia Sodha was the other one I think.

Yes, no one was allowed to ask the difficult questions. But SOMEONE should have been asking them, and a long time before the study got this far.

Seriously though, the human behavioural studies that I carried out were so tame, and the rigor that was required to get ethical approval for them was fierce. This abomination seems to have been waved through by people with blindfolds on and their fingers in their ears singing “lalalala”.

DrBlackbird · 30/11/2025 10:24

ProfessorDameFarriersGirl · 30/11/2025 10:07

I came across this link on another thread but its relevant here. Kings College are not only captured but it seems heavily invested in embedding trans activism and overturning the prohibition on puberty blockers for children. Not exactly an impartial partner in this trial.

https://www.transgendertrend.com/gender-activism-nhs/

That report of the conference is extremely worrying.

Including reports of how Professor Clive Kay and Dr Michael Brady - who are such high profile and influential men within the NHS - continuing to proselytise and insist on pushing through medical treatments that have attracted both anecdotal and empirical evidence of harm. Doesn’t feel like affirmative ’gender care’ is going to stop anytime soon. Heartbreaking.

It’s also concerning how much Wes Streeting is trying to play both sides here. I wonder what he really thinks when no one else is there.

nicepotoftea · 30/11/2025 10:37

Haven't societal beliefs and expectations changed in other ways?

Certainly in the late 90s and early 2000s and perhaps in 2011 you could have argued that this treatment could be life saving, and that the likely end for any non-passing trans person was an early suicide. The goal of all legislation and treatment was concealment.

However, the increase in numbers of people identifying as trans without having taken puberty blockers, including people identifying with a gender not even recognised in law undermines the idea that being trans is life threatening.

Slothtoes · 30/11/2025 10:40

TheWeightOfTheWorld · 29/11/2025 12:45

@OpheliaWitchoftheWoods And when a prepubescent person reaches adulthood with a child's physiology, they will presumably no longer have the protection of laws which automatically deem it illegal to have sex with a child, although they still retain that body.

Edited

Exactly. This is a real safeguarding issue- if these ‘treatments’ in fact create a group of highly vulnerable adults (in legal terms adults). If this is what is happening- (and why wasn’t this the toppermost thing on GIDS’ list to research, and for the UK research regulators to force GIDS to research?) then that would be appalling abuse of the most fundamental lifelong kind of already distressed kids. That would be actual genuine ‘transphobia’. How is this not an urgent question at PMQs, news item etc. Hundreds of young people been given a very controversial potentially life altering set of drugs then allegedly lost to follow up.. within NHS records.

Slothtoes · 30/11/2025 10:44

NRTFT and just seen comments that they seem to be selecting out the informed gender critical journalists in discussing this. WTAF?!

The tide has definitely not turned if this dangerous selection of questions is still acceptable in any press briefing

OpheliaWitchoftheWoods · 30/11/2025 10:58

Further evidence that if done openly, honestly and without bias they know they could not get it through . The deceit and control of the message is necessary to sustain the bias.

I honestly despair at our current political leaders and the world they are so busily creating.

lcakethereforeIam · 30/11/2025 11:38

This bit stuck out to me

Cass insisted she did not blame parents who chose to seek drugs for their children from alternative sources. “We have to acknowledge that parents are doing their best to do what they think is right for their children. They’re not setting out to subvert a system, they’re parents who have been let down because they’ve been so long on waiting lists that they’ve become desperate and have gone to seek help where they can.”

She seems terribly naive about the parents, or carers/social workers as 'looked after' kids seem to be over represented in the gender confused. The parents, etc. should be part of the preliminary investigations before any child is considered for this horror story.

MalagaNights · 30/11/2025 12:00

TwoLoonsAndASprout · 30/11/2025 09:58

Ok, so, I’m an ex-academic, have spent a stupid amount of my life designing research studies, and teaching students how to do the same, and evaluating those of other researchers. It is clear that the Pathways trial is the most flabbily designed piece of shit ever. I think we’ve established that.

But! What bothers me most is this: what is the goal? I mean, “make these children happier,” sure, but what does that mean? If it is just “alleviate depression,” well, we have drugs for that - drugs that don’t have the diabolical side effects of puberty blockers. So it can’t be that.

The goal must be “remove their perceived gender incongruence.” But what does that mean? It can only mean somehow bring their mental picture of themselves, and their physical body, into a state of congruence.

Which means one of two things. Either help them to accept their sexed bodies as they are, using tools that address this as a mental health or psychological issue. Or cosmetically alter their body to make it match their mental picture.

Puberty blockers do not help a child accept their sexed body. We know this. The flawed data collection from the Tavistock showed this. They lead in 90% or more of cases to a desperate desire for cross-sex hormones. They prevent the brain development that happens in puberty that would allow for a child to mature and realise that there is nothing wrong with their sexed body.

So, by default, this study is starting from the standpoint that the solution to “gender incongruence” is to permanently cosmetically alter a perfectly healthy child’s body.

The study is biased and broken before you even get to the fact that the design is beyond flawed and won’t give any useful results at all, and will physically harm vulnerable children.

How Cass can look anyone in the eye and say that this study is necessary is beyond me.

This sums up exactly what I've been trying to say.

What is the aim here?

And why isn't the aim for children accept their healthy bodies? Measure that.

MalagaNights · 30/11/2025 12:08

lcakethereforeIam · 30/11/2025 11:38

This bit stuck out to me

Cass insisted she did not blame parents who chose to seek drugs for their children from alternative sources. “We have to acknowledge that parents are doing their best to do what they think is right for their children. They’re not setting out to subvert a system, they’re parents who have been let down because they’ve been so long on waiting lists that they’ve become desperate and have gone to seek help where they can.”

She seems terribly naive about the parents, or carers/social workers as 'looked after' kids seem to be over represented in the gender confused. The parents, etc. should be part of the preliminary investigations before any child is considered for this horror story.

The parents will be a self selecting group, not a random selection of people with distressed children.

I would presume they'll all believe in gender ideology. Which is a belief system.

Can you imagine if any other religious group were seeking dangerous drugs to alter children's bodies as part of their belief?? They would probably be imprisoned instead of given trials to see if their belief was real.

MalagaNights · 30/11/2025 12:13

They should be collecting data on the parents who seek this treatment. Their views and beliefs.

I presume they'll skew left and progressive, and this will be an important part of their own identity.

They'll subscribe to beliefs embedded in queer theory.

So children from particular religious or political backgrounds will be more at risk of this dangerous medicalisation.

That should sound some enormous fucking great alarm somewhere.

TwoLoonsAndASprout · 30/11/2025 12:26

Here’s another question to throw out to the void:

What exactly was Cass’s role in the production of the Cass report?

By which I mean, I know she didn’t personally conduct the systematic reviews - those were done by (I think) researchers at the University of York.

But did she even write the final report? Or did she somewhat supervise someone else writing it?

Because the way that she is currently talking about these studies (both the ones in the systematic review and the Pathway one) is starting to feel very much like some professors I knew who would present the work of their PhD students without really understanding (in as much depth as the student) the work.

She doesn’t sound so much like an ideologue as she does like someone who - while very intelligent and well-versed - simply doesn’t have the depth of knowledge that I would have expected of someone who had conducted the work themselves. She constantly sounds like she is going on what someone else told her about something.

Is it just me?

lcakethereforeIam · 30/11/2025 12:29

I'm getting 'be kiiind' vibes.

MrsOvertonsWindow · 30/11/2025 12:46

TwoLoonsAndASprout · 30/11/2025 12:26

Here’s another question to throw out to the void:

What exactly was Cass’s role in the production of the Cass report?

By which I mean, I know she didn’t personally conduct the systematic reviews - those were done by (I think) researchers at the University of York.

But did she even write the final report? Or did she somewhat supervise someone else writing it?

Because the way that she is currently talking about these studies (both the ones in the systematic review and the Pathway one) is starting to feel very much like some professors I knew who would present the work of their PhD students without really understanding (in as much depth as the student) the work.

She doesn’t sound so much like an ideologue as she does like someone who - while very intelligent and well-versed - simply doesn’t have the depth of knowledge that I would have expected of someone who had conducted the work themselves. She constantly sounds like she is going on what someone else told her about something.

Is it just me?

We know that Gendered Intelligence & Mermaids exerted massive control over child healthcare at GIDs resulting in its closure. They and other queer theory lobbyists have self identified as experts in so many professions despite having zero qualifications / expertise. So it's not beyond the realms of possibility that some of the dangerous men heading up numerous queer theory pressure groups in & outside the NHS have been able to persuade her that she just doesn't understand the issues?
It's happened to countless politicians, academics and leaders so could have happened to her as well?

TwoLoonsAndASprout · 30/11/2025 12:50

lcakethereforeIam · 30/11/2025 12:29

I'm getting 'be kiiind' vibes.

But also, where is her intellectual or academic curiosity?

Like, you presided over something as in-depth and damning as the Cass report, but when this new trial pops up and it looks like it’s got the scientific rigour of a pineapple and would definitely have been thrown out as poor quality by the systematic reviews that you yourself presided over, you shrug and say well, you know, what can you do?

Really?

moto748e · 30/11/2025 13:43

DrBlackbird · 30/11/2025 10:24

That report of the conference is extremely worrying.

Including reports of how Professor Clive Kay and Dr Michael Brady - who are such high profile and influential men within the NHS - continuing to proselytise and insist on pushing through medical treatments that have attracted both anecdotal and empirical evidence of harm. Doesn’t feel like affirmative ’gender care’ is going to stop anytime soon. Heartbreaking.

It’s also concerning how much Wes Streeting is trying to play both sides here. I wonder what he really thinks when no one else is there.

Just read it and couldn't agree more. The level of capture in the higher reaches of the NHS is very worrying.

TheWeightOfTheWorld · 30/11/2025 14:08

Clive Kay is retiring from King's in the summer.
https://www.kch.nhs.uk/news/kings-chief-executive-clive-kay-announces-retirement-from-role/

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