It has obvious flaws and has been debunked. Basically it is arguing Cass should have used a bunch of extra low evidence reports, while failing to turn up any high quality evidence the Cass reviewers missed. So this just reinforces the Cass Report we already knew there were lots of bad science claiming false things. Just turning up MORE weak evidence doesn't show anything.
Detailed examination
https://www.reddit.com/r/BlockedAndReported/comments/1kk0fnj/critically_appraising_the_cass_report/
Cass doesn't need to worry.
Some background
Main author -- "The author of this paper, Dr. Chris Noone (he/him) is a Psychologist, who's research subject is "experiences of health and wellbeing in the LGBT+ community". He lectures in the College of Arts, Social Sciences and Celtic Studies at the tiny, but very pretty, University of Galway on the west coast of Ireland. He has several papers on mindfulness. Veterans might remember him from pre-Elon Twittex where he specialised in having his arse handed to him."
"If you look at the authors its the exact same scenario as seen with Stanford and all these other critiques, I could easily publicly find the sexuality/gender identity of 14/21 researchers:
-Florence Ashley - openly Trans radical activist from Canada covered in the Mail for pushing blockers
-Natacha Kennedy - openly trans self-described "bolshy trans woman" - was accused by The Times and Spiked of running a smear campaign against trans critical academics
-Rachel Heath - openly trans
-Dori Grijseels - openly trans
-Alex Southgate - speculative but does appear to have written letters to Stonewall (activist) as trans identifying
-Ed Kiely - they/them researcher in feminist geography with focus on geography of gender affirming care
-Jo Hartland - self-described "queer/they/them"
-Quinnehtukqut McLamore - they/them researcher on gender affirming care
-Chris Noone - self described "queer" - specialist interest in LGBT research and health equity.
-Alex Ashman - they/them advocate for gender affirming care
-Ryan Goulding - Self-described they/them
-David Comer - Age 25 - HIV researcher with focus on LGBT space, very much appears to be gay (attending pride, casually using the word "queer", progress pride flags etc)
-Duncan Shrewsbury - Brighton based self-described "queer" GP
-Dr John Gilmore - self-described gay he/they"
Given this is a paper dealing with ethics and statistics, do you not think at least 66% of the named researchers coming from demographics seen in max 5-10% of the population is highly improbable by chance occurrence? No less than 5 being nonbinary and 5 being trans? Do you not see any risk of bias here?"