A recent article from the US discusses the issue of social constructs arising from the physical reality of a person's body.
https://www.nbcnews.com/news/asian-america/race-change-to-another-trend-online-rcna93759
The article is discussing transracialism, but many of the forcefully-put arguments will he well familiar to those on this board insofar as they also relate to gender.
One of the interesting nuggets is a statement that:
The modern concept of race is inseparable from the systemic racial hierarchy hundreds of years in the making. Simply put, changing races is not possible, because “biological races” themselves are not real.
This seems to be a perfect analogue for gender, that while sex is real, gender cannot be separated from hundreds (thousands?) of years of hierarchy, and that genders themselves aren't real.
I'm really interested that in the US, such a statement can be so blatantly stated, but one would not be able to say the same about sex (or indeed gender) in the same way.