The good news is that as an autistic person she may well be quite open to logic and fairness as we do tend to believe that the same rules should apply to everyone. So here's my suggestions to pass along to her parents to consider if they feel they are brave enough / appropriate to share with their dd
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Emphasise the existence of Gender Identity AND Sex and the fact they they are different words meaning and describing different things.
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Gender Identity is how she feels, her personality, her likes and dislikes. Encourage her to describe how's she's feeling and try to expand and develop emotional vocabulary.
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Sex is the sex of a person's body. Sex is binary and doesn't change.
A person can control a number of aspects of their appearance though. Whatever your position on makeup, haircut, dress, choice of clothes the sex of the person remains unaltered. Medical interventions do not change your sex. Some medical interventions carry substantial health risks and have be painful, intrusive and have both long and short term adverse side effects. These interventions DO NOT change your sex but can impact on your appearance.
Arguments to consider against a girl / female taking puberty blockers
Lower bone density.
Does she want to grow up to be strong and athletic? Is being weaker than the average women and /or walking on crutches an outcome that seems a sensible risk?
Less development of genital tissue, which may limit options for gender affirming surgery (bottom surgery) later in life.
Keeping your options open for a more effective and successful surgery she may well want in adulthood is a completely valid reason to decline puberty blockers.
Impact potentially permanently (lowered or absent) sex drive
Telling her that regardless of her gender identity the adults who care about her want her to grow up into (in so far as is possible) a happy fulfilled adult who is comfortable with their sexual orientation, and can enjoy fulfilling sex with a partner who loves them, is a perfectly good and valid reason to not pursue / obtain puberty blockers.
Body building / exercise can certainly have at least as much success in changing how you appear whilst being a demonstrably good impact on overall health.
- In 2011 an estimate by GIRES said "Only 20% of the UK transgender population were likely to seek medical treatment for their condition at some stage" By 2016 Self identification had grown much more commonplace and "only 2.8% of the transgender community is undergoing any gender-affirming treatment with the vast majority 97.2% simply self-identity with no modifications to their sexed body whatsoever."
source* *https://fairplayforwomen.com/penis/
It may therefore be useful to emphasise that there is no single right way to be a trans man and whilst it is totally reasonable for her to describe her GI in the terms she feels are most helpful in explaining her feelings it doesn't follow at all that her body needs to be chemically or surgically altered to align better with that gender identity, and certainly that there is absolutely no rush to head in that direction.
Also there are two schools of thought within Transgender Activism as to whether a persons Gender Identity is inate and fixed or is actually much more fluid allowing more validity to non-binary and gender fluid feelings. Not doing anything drastic (and drugs which disrupt puberty are a drastic option from the point of view of your health) until she knows who she feels about it in 10 years time is a perfectly valid and sensible option.
Stonewall definitions below
Transgender man - "A term used to describe someone who is assigned female at birth but identifies and lives as a man. This may be shortened to trans man, or FTM, an abbreviation for female-to-male."
ALL she or anyone needs to do ACCORDING TO STONEWALL to be a trans man / transman / Transgender man is to recognise that that is the descriptor label which suits her best in her opinion. And then to 'live as a man' discuss precisely what that involves in her opinion.
Gender expression - "How a person chooses to outwardly express their gender, within the context of societal expectations of gender. A person who does not conform to societal expectations of gender may not, however, identify as trans. "
Not all men present in stereotypically masculine ways. Similarly there is no obligation for her as a trans man to be stereotypically masculine all the time. What clothes make her most comfortable and happy?
Non-binary - "An umbrella term for people whose gender identity doesn’t sit comfortably with ‘man’ or ‘woman’. Non-binary identities are varied and can include people who identify with some aspects of binary identities, while others reject them entirely."
Pip Bunce said: "For me, being gender fluid means I am non-binary, at no fixed point on the gender expression spectrum. I personally have no desire to transition — it doesn’t affect my physical makeup, whereas for others that identify the same, they do wish to transition — there really are no hard and fast rules as these are only labels." https://www.standard.co.uk/news/uk/gender-fluid-exec-named-on-list-of-top-100-women-in-business-a3942896.html
Trans - An umbrella term to describe people whose gender is not the same as, or does not sit comfortably with, the sex they were assigned at birth.
Trans people may describe themselves using one or more of a wide variety of terms, including (but not limited to) transgender, transsexual, gender-queer (GQ), gender-fluid, non-binary, gender-variant, crossdresser, genderless, agender, nongender, third gender, bi-gender, trans man, trans woman, trans masculine, trans feminine and neutrois.
It is unlikely that she is comfortable with all aspects of a stereotypically male existence. It is also likely that she may feel more comfortable imagining herself as possibly moving between a spectrum of non-gender conforming man, non-binary, genderless, trans masculine and agender. Suggest she'll need time to consider her options but in the meantime the priority is her health not her appearance.
https://www.stonewall.org.uk/list-lgbtq-terms