Different skeletons, muscle amounts and types, hormone levels, blood and loads more.
I think the point PP was making is that the lady brain myth is nonsense.
Yes, I saw that. If we rephrase it as "There is no evidence that female and males are fundamentally different beyond primary and secondary sex characteristics" then it would be true, but trivially true. Because it's the differences between these characteristics which define the two sexes. So it's actually tautologous.
Yes exactly. Sex hormones, particularly androgenisation affect humans quite profoundly. Embryos start off as sexually undifferentiated. Primary and and secondary characteristics, skin, hair, muscles, cartilage, bones, hearts, lungs, faces… the entire body is affected by sex hormones right through the life course. The idea that the brain wouldn’t be affected at all these stages by different sex hormones seems implausible. Developmentally and permanently.
To a large extent sexual behaviour is driven by neural pathways in the brain and they develop differently under the influence of sex hormones. The entire body is differentiated by these hormones so why wouldn’t that include the brain? I’m not saying that’s all we are. But equally that doesn’t mean it has to be dismissed by reductio ad absurdum to ‘lady brain’.