Long-term effects of gonadotropin-releasing hormone analogs in girls with central precocious puberty

[Bespin]

here is a study about the long term effects of pubity blockers on young people I know people are concerned about that. would be interested in peoples veiws about the findings.

www.ncbi.nlm.nih.gov/pmc/articles/PMC4342775/

I have never seen one of them bother to address Tammy.

Batteriesallgone

That is indeed an excellent point.

If the only reason you're giving these drugs to children is the alternative is suicide, that's the contraindication right there.

I'm not a scientist. But I recognise logic when I see it.

Bespin how does that fit with your opinion?

How is gender dysphoria not a mental illness. Mentally healthy people arent suicidal which apparently half of trans people are

tammy

February 2017 article:
'Drug used to halt puberty in children may cause lasting health problems'
(extract)
"For years, Sharissa Derricott, 30, had no idea why her body seemed to be failing. At 21, a surgeon replaced her deteriorated jaw joint. She’s been diagnosed with degenerative disc disease and fibromyalgia, a chronic pain condition. Her teeth are shedding enamel and cracking.

None of it made sense to her until she discovered a community of women online who describe similar symptoms and have one thing in common: All had taken a drug called Lupron.

Thousands of parents chose to inject their daughters with the drug, which was approved to shut down puberty in young girls but also is commonly used off-label to help short kids grow taller.

The drug’s pediatric version comes with few warnings about long-term side effects. It is also used in adults to fight prostate cancer or relieve uterine pain and the Food and Drug Administration has warnings on the drug’s adult labels about a variety of side effects.

More than 10,000 adverse event reports filed with the FDA reflect the experiences of women who’ve taken Lupron. The reports describe everything from brittle bones to faulty joints.

In interviews and in online forums, women who took the drug as young girls or initiated a daughter’s treatment described harsh side effects that have been well-documented in adults.

Women who used Lupron a decade or more ago to delay puberty or grow taller described the short-term side effects listed on the pediatric label: pain at the injection site, mood swings, and headaches. Yet they also described conditions that usually affect people much later in life. A 20-year-old from South Carolina was diagnosed with osteopenia, a thinning of the bones, while a 25-year-old from Pennsylvania has osteoporosis and a cracked spine. A 26-year-old in Massachusetts needed a total hip replacement. A 25-year-old in Wisconsin, like Derricott, has chronic pain and degenerative disc disease.

“It just feels like I’m being punished for basically being experimented on when I was a child,” said Derricott, of Lawton, Okla. “I’d hate for a child to be put on Lupron, get to my age and go through the things I have been through.” (continues)

www.statnews.com/2017/02/02/lupron-puberty-children-health-problems/

for Tammy.

Thanks all. It’s okay. I was an adult, I consented to the treatment, I take responsibility for continuing it when it wasn’t licensed for longer term use.

I could not live with myself if I caused this sort of pain and misery to my child.

They can transition as adults, just as generations of trans people have done before. But apparently your child being more likely to pass is more valuable than protecting your child’s health. It’s sickening.

TammySwansonTwo

It is so appalling that both your experience and concerns are ignored.

But apparently your child being more likely to pass is more valuable than protecting your child’s health. It’s sickening.

This is the crux of it. 'Passing' needs to be addressed. Because it's all about what other people think of you.

It's considered far more important than your own infertility and having a satisfactory sex life.

The superficiality is difficult to believe.

Tammy it's incredibly impressive that you have channelled the difficult feelings about what's happened you, into a forward trajectory to help others. I'm always impressed by your strength and determination.

I take responsibility for continuing it when it wasn’t licensed for longer term use.

Legally and ethically, the responsibility lies with the prescriber.

Tammy it's incredibly impressive that you have channelled the difficult feelings about what's happened you, into a forward trajectory to help others. I'm always impressed by your strength and determination.

This. Kudos to Tammy.

If the only reason you're giving these drugs to children is the alternative is suicide, that's the contraindication right there.

This. It is clearly a mental health issue whatever position trans rights lobbyists have steamrollered through.

I have some anger, not towards my consultant who discussed with me at length before I decided to continue. It was the first time in over a decade I’d been mostly free from pain and anything that might happen to me felt worth it at the time. Hindsight is a wonderful thing, and these parents won’t have it until it’s too late.

The anger is for doctors who are willing to prescribe drugs with severe side effects but have precisely zero interest in helping you when those drugs obliterate your life. No investigations, no attempts to improve things, just an umbrella diagnosis with no treatment and a shrug. I really fear for these children - my mental health was reasonably robust. It’s not any more.

A mental health professional? WTAF?

Endochrinologist Dr Michael Laidlaw's evidence at a recent California Senate Committee:

www.youtube.com/watch?time_continue=1&v=0Lu1r1pyGFc

see:
twitter.com/MLaidlawMD/status/1012822866369208320

Is this treatment maybe a cheaper alternative to good quality mental health treatment for these young people?

I read this news report of a trial in the Netherlands that has been stopped because of an unexpectedly high number of baby deaths (I found the report quite upsetting TBH)

www.theguardian.com/world/2018/jul/24/eleven-babies-die-dutch-women-viagra-drug-trial

The end of the report is a quote from a doctor:

“In the Netherlands, doctors are reasonably cautious. The effectiveness and safety of a drug must first be rigorously demonstrated through placebo-controlled studies before we prescribe it. Justly. That has only been demonstrated once again.”

Quite.

Thanks Tammy from a mum whose daughter has been caught on this ideology when it's obvious there are other worries with her mental health. A thousand thanks 💐🌺🌻

You’re very welcome Ovula - I’m so sorry she and you are having to deal with this. My son is currently being investigated for autism and I’m terrified of having to face something like this down the line, but I know 100% there will be no GnrH analogs for my children while they are minors.