I have been suffering with bad anxiety for the the last few months and I am due to start sertraline. I came off the depo in October and have gone back on it again on Tuesday (14th). Have been on and off it a couple times for the past 7 years with no issues and I love it because I don't get a period. I am having some side effects at the minute (spots and mood swings - nearly burst into tears because my tv wasn't working before lol) and was wondering if anyone else had the same experience and how long it lasted? I don't remember it being like this last time but I either don't remember or wasn't paying much attention. I was also wondering if it's worth waiting a week or two until my body gets used to the depo before starting sertraline so my mood swings aren't as bad? I have been on sertraline before and remember it was quite rough for the first couple weeks but I eventually got on okay with it. Any advice welcome :)