Never realised about the animal cruelty aspect of weightloss injections

[StripeyKnickersSpottySocks]

Saw an article yesterday about monkeys getting force fed in order for WLI to be tested on them. The monkey looked really distressed. Feel absolutely sick. I’d just assumed there had been human trials, never thought about monkeys.

Does anyone know if it’s all WLI or have some never been tested on animals?

FFS. It’s a diabetes medication. If your 2 year old developed diabetes would you choose a) the drug that has been fully tested, including on animals, and is known to be safe, or b) the one that had undergone no testing whatsoever?

Calpol - tested on animals. Chemo drugs - tested on animals. Utterly stupid to think not testing is a good idea.

I'm not saying testing isn't a good idea. But not testing on animals is a better one. Where is the proof that a drug would work the same way on a monkey as it would a human?
So why not test solely on humans? We have hundreds of prisoners that are never going to come out of prison. At least the results would be more accurate. Test on them instead.
Or is it a case of, oh well, they're just animals, if they die, it doesn't matter?

I'm aware that some of the medication I am taking, will have been tested on animals in the past, there's not much that can be done about that now, but we should have moved on from torturing animals.

And I think the majority of WLI are being used for vanity, bought, not correctly prescribed by a GP, rather than as a medical intervention for diabetes. Let's not kid ourselves there.

While WLI may be being bought by those wanting to lose weight, they are in fact diabetes drugs. The fact that they can be used to lose weight is secondary.

As for testing on prisoners - really? Do you honestly think that removing prisoners human rights is ok? Rape a prisoner - perfectly fine. Cut a prisoners arm off - perfectly fine. Not to mention the multitude of issues around the health of the prison population that would invalidate the results, if they managed to get any.

Oops you’re only incarcerated because you didn’t pay your council tax, never mind! Oops you’re John Malkinson and falsely imprisoned. Never mind!

Maybe you think any drug which has a secondary use to treat something you regard as due to lifestyle should be withdrawn from the market? So no Mrs Smith you can’t have that breast cancer chemo because the same drug can be used for lung cancer which is the patients fault for smoking.

@titchy You're being ridiculous now.
I didn't say test on Harry who's only in for car theft. I'm talking about prisoners who have a whole life tariff or will die in prison because their sentence will outlive them.
Prisoners rights?! You're having a laugh! They should have thought about the rights of the people they've committed heinous crimes against! They don't have the right to have rights at all. They gave up that privilege when they committed the crime.

The tests on animals are not testing that the medication works as intended in humans, it's specifically for toxicity and safety.

The large majority of private WLI prescriptions are being used to treat obesity and overweight with a weight related health condition. They are bought in the same way that NHS prescriptions are bought, in that they are paid for and it's just the cost that varies. They are correctly prescribed, either by a doctor or by a qualified prescribing pharmacist.

Again, a ridiculous comparison. 🙄

Ok so no mouse testing. There aren’t enough prisoners in the world, let alone the UK, to substitute for all the mice used. So what’s your solution?

But you’re the one objecting simply because it’s a WLI - you’ve conveniently ignored the fact that these drugs are for diabetes and that weight loss is a by-product - they weren’t developed as weight loss drugs.

Yes, this is true, but not all new medicines are tested on highly intelligent animal species such as monkeys. There is a hierarchy of animal testing - the first being rodents (most medicines are only tested on mice/rates), then dogs/pigs/rabbits, and monkeys are last. It is actually quite difficult to gain approval to test on monkeys, it has to be shown to be medically necessary. I'm not saying this hierarchy is right or ok, but it is what it is.

I'm not saying testing isn't a good idea. But not testing on animals is a better one. Where is the proof that a drug would work the same way on a monkey as it would a human?
So why not test solely on humans? We have hundreds of prisoners that are never going to come out of prison. At least the results would be more accurate. Test on them instead.
Or is it a case of, oh well, they're just animals, if they die, it doesn't matter?

Oh my gawd. They walk amongst us. 😂😂

Judging by your pointless comment, yes they do.

Come on! You must be embarrassed by your post? I was embarrassed just reading it.

Or…it’s half term already?

@AuntChippy Not at all. I stand by what I said. If it embarrassed you so much, I feel quite sorry for you.
Do you actually have anything interesting to say or do you just like to pick on posts and try and humiliate people? Actually, don't bother answering, I think I know the answer, so there's no point in further engagement. Have a great evening.

The punishment of a prison sentence is loss of liberty, the sentence does not include abuse of human rights, we would be just one step away from nazi germany during the 2nd world war, where is your moral compass??
lots of medicine is tested on animals before humans, New medicines currently tested on animals include treatments for Alzheimer's disease, cancer, diabetes, and infectious diseases, as well as novel gene therapies. Animal models, primarily mice, rats, and non-human primates, are mandatory for safety and toxicology assessments, such as evaluating reproductive side effects, before human trials. This will not change until humans become more altruistic and begin volunteering for trials, will you be first in the queue?

Humans do volunteer for trials, in Phase 1. This is after all the animal testing has been done. You do not get clearance to start testing on human volunteers until the safety and toxicology has been done.

The potential way out is if our in silico modelling one day becomes good enough to predict effects in humans better than animal trials do. The other is if we can build organoids of some kind that also predict those effects better than animal trials.

But so long as animal trials are the best approximation of the effect on humans of drugs, no sane regulator on the planet will allow you to start giving drugs to humans without having tested them on animals first.

Or is it a case of, oh well, they're just animals, if they die, it doesn't matter?

Actually, it's often a case of we are going to kill them at the end in order to dissect them and study the effect of the drug on their internal organs....

Do you steer clear of all medications?