Wondering if it was a bad idea doing wli

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I started taking mounjaro as I was desperate, my weight kept going up and up and I was obese. I just couldn’t get a handle on it.
i have yo yo’d all my life, and have mostly been overweight and I've got older it went went from hovering at overweight to hovering at near obese until I was.

Im now the slimmest I’ve been in years, finally a healthy weight. I’ve been strength training for a year. I would like to come off mounjaro. A friend of mine came over and has gained two stone back in three months.

i would like to come off, but the evidence is showing im going to gain it back even if i stick to a calorie deficit and the gym.

I don’t want to go back to being overweight, im also terrified of potentially relying on this drug.

I originally said I’d try it for 3 months. It’s now a year later.

sometimes I wonder why couldn’t I just do it the natural way and resort to this. Because now I wonder if I’m tied to always taking this. I don’t want to be reliant.

I apologise for the ramble, im panicking and apart from my friend, no one else knows in my life so have no one to talk to

Obesity is a long term condition that needs to be managed for some of us. I think the prevailing view now is that if you have been obese ‘forever’ in all likelihood then you will be taking MJ for the long term.

I am not quite in maintenance yet but I am expecting that to be the hardest part in terms of tritating down and seeing how I can manage. I might be very lucky or I might end up on MJ for many years yet in which case I will be buying a pen on a regular basis.

There is a thread on here for those of us who have gone cold turkey.
Off MJ completely hopefully that link works! Similar levels of worry and success compared to other maintenance methods but you can see not everyone piles it back on.

Most obese people will have done numerous diets throughout their lives and put the weight back on. This may happen quickly or gradually, depending on their eating habits. Mounjaro is no different - if you come off the medication, you no longer have medication helping you to stay in a calorie deficit.

I was on Mounjaro for six weeks and had to come off for medical reasons (hoping to go back on eventually). I could feel the medication still having an effect on my eating habits for about three weeks after my final jab. When it finally ran out, I started desperately craving sugar and carbs, and eating past fullness again. It was incredibly depressing to go back to 'normal', because it's so bloody hard to overcome the hunger and cravings - and that's why I'm obese. I've been trying really hard to eat like I was on MJ, and I've gained 2/3 pounds in eight weeks. I'm not piling it back on... but I know exactly why I've gained weight.

Well then I'll just stop bothering then shall I. Probably be one of the 80% according to some random on mn, so what's the fucking point. Honestly this is the attitude I've been working on sorting out while I used the medication. Cheers for the positive input. 👍

Hey there, this actually one trial where the participants after coming off the WLI were able to maintain the weight loss (that I know of). In most trails the participants regained the weight.

The whole talk is worth watching, but the relevant trial is discussed about 28 mins in.

The study McKenzie AL, Athinarayanan SJ. Impact of Glucagon-Like Peptide 1 Agonist Deprescription in Type 2 Diabetes in a Real-World Setting: A Propensity Score Matched Cohort Study. Diabetes Ther. 2024 Apr;15(4):843-853. doi: 10.1007/s13300-024-01547-0. Epub 2024 Feb 29. PMID: 38421559; PMCID: PMC10951146.

@Raccoonswillonedayrevolt that's an interesting study, but it did look specifically at people with T2 diabetes who were on a GLP1 but then had that discontinued and were moved onto a carbohydrate restricted diet with continual support delivered via telemedicine, so presumably regular video/phone support.

There's another study that was reported on earlier this year, which has yet to be peer reviewed and published. It looked at a lot of data from US medical records and analysed the long term weight of people who had used a GLP1 and then stopped. It found that about a third kept the weight off, about a third lost some more weight and about a third put weight back on.

https://www.drugdiscoverytrends.com/the-forever-drug-assumption-about-glp-1s-may-be-wrong-according-to-nference-analysis/

The results may not be robust or have some important caveats, but it's a fascinating read nonetheless.

If you're in a calorie deficit you wont gain weight with or without WLI, thats not possible.

If you stick to your maintenance calories then you'll stay the same. This is really individual regardless of what TDEE calculator say. Often people miscalculate the level of exercise they really do.

Like after any diet, people gain weight as they go back to old habits, its not specific to WLIs. Without staying on a low dose you are always relying on ensuring you control what you eat and how much. People seem to have a real negative attitude towards WLIs and regaining but its no different to any other diet. Using WW or SW is no different,even though you are using willpower a high % regain as they stop going to weekly classes so lose the support (similar to stopping WLIs).

For those WLIs are helping with medical conditions obviously it is slightly different and it is recommended you have maintenance doses. The maintenance pharmacies have support plans in place for however you decide to do it though, whether cold turkey or low dose.

I've maintained (and lost more) since stopping in December 2024.

Of course, people will regain, same as any weight loss, if they don't do things to maintain.

Ignore. I tend to think these posts are from people who WANT you to fail, probably because they struggle to manage their own weight so they want everyone else to as well - or else, it shines a light on why they can't...

It's perfectly possible to maintain if you are willing to make a change and put the effort in.

I do wonder if they go on any other threads for slimming world or weight watchers to troll the same kind of rubbish 🙄

Well no, I’m on mounjaro, and have been for two years, maintaining for a year. I made the comment.

the point I was making was 3 months after coming off is still very early, and it will take a lot of hard work. The poster is doing well. I was not remotely suggesting she shouldn’t bother, just simply 3 months is not the teller, it is too early.

I think the post has been misinterpreted as the poster attacked in response. I’m very pro weight loss injections, obviously, I’m not coming off. So as pro as it gets, but simply I don’t think much can be taken from only being off a few weeks

life and diet fatigue sets in, if course it’s worth trying and the poster can even go back on, but again, I simply feel 3 months is too early to give an indication on regain as it’s still the novelty period.

i only did 6 weeks on MJ as couldn’t take the heartburn and felt like I had pregnancy morning sickness 4 days week . I did though use that short period to totally change habits - stopped grabbing that toastie or cheese and ham croissant with a coffee in the morning, cut out cakes, biscuits entirely( I don’t eat chocolate or crisps often at all but never did) I drank more water, learnt to love Greek yoghurt, salted popcorn, prawn salads, Longley farm cottage cheese, hard boiled eggs, porridge . Cooked from scratch more and serve myself about a third less than my H . I’ve lost 2 stone in 11 months, 2 stone still to go- I suspect it would be faster if I gave up my half a bottle of wine on both a Friday and Saturday night and I also eat what I want on holiday too ( so gain about 2.5kg every time- which is 3 or 4 times a year, mainly alcohol I think and more salty food ) - I’ve done it hard core but basically kept up the habits that MJ gave me - am I hungry sometimes, yes , but I grab an orange or a banana and a small bag of popcorn (88 cals) and drink a small bottle of water . I don’t have starters or deserts either if we go out, stick to a main and maybe a small bit of bread and butter and olives. I also popped in 2 excercise classes a week, one is a dancing routines group which I’ve enjoyed a lot and made some nice friends. I do think boredom is a biggie too, so now always have a book on the go or do 20 minutes dancing to Alexa in the kitchen and the urge to go in the fridge goes.

Interesting, I hadn't seen that.

I don’t really understand.

You are taking the medication to correct your obesity, which causes high risk health problems. Why would you worry about continuing to treat that condition when the medication is working?

Would you stop taking high blood pressure meds, or epilepsy medication?

Yep, why us middle aged women lose easily on mounjaro . I could not eat but it never worked, low dose of mounjaro and boom, weight drops off.

I’m worried about the long term implications of using this, I would happily use this but can’t help wondering if it’s going to bite me in the arse one day.

I worry about this too. Glp1 has been used for a long time at low doses for diabetes. But mounjaro specifically, is new and the safety data is being collected in real time. I love how much weight it has helped me lose but i alao feel like a ginuea pig!
I am trying to reverse diet and taper to a low dose. Scared to be on mj forever but more scared to come off it yet!

Mounjaro as a brand is new the active ingredients have been about for decades and the trial datacarries across.

i am genuinely surprised how many people don’t understand the difference between active ingredients, brands etc and think all the world health authorities approve medications and let the public be guinea pigs. Surely even common sense would tell you that wouldn’t happen and you’d spend some time googling at least?

World health authorities have approved drugs which have later found to be harmful. Surely common sense would tell you that, and you'd spend sone time googling at least, rather than your patronising response.
People can enjoy the benefits of mj, whilst having concern about long term effect. Both can exist at the same time.

Hi, I’ve come off and am maintaining well. Tbh I established new eating patterns on WLI and without the distractions of food noise I cut down my portions and concentrated on nutrition and meals focussed around mostly protein and fibre. Now I’m not on WLI I still eat the same way but have reintroduced breakfast. I don’t feel like I’m on a diet at all and my weight has never moved more than 2lb up or down.

Started MJ in august at 2.5, did go up to 5 for i think 2 months (might have been 1 🤔)

i went down to 2 for 5 weeks and i have just had a month at 1.5. My plan is to try and come off completely but it might be that i sit at 1 for a long time 🤷🏻 i am in a calorie deficit at the moment but i do indulge more on some occasions so it does all balance out over the week (usually)

i have lost 2 stone and have tried to change some of my eating habits, thats a lose of about a pound a week and more to be honest than i planned

i know it will be much harder for me without MJ but i don’t really see how i will gain if i continue to eat this way. I do love the size i am now but i would be ok a stone heavier ….i would be beyond disappointed at gaining it all back

When did you come off? Always like to hear real life experiences