My 6 year old Ragdoll used to be so well litter trained until decided last year that he only wanted to go in a corner of the living room behind a chair. I've tried cleaning with enzyme cleaner, put a second litter tray beside the 'chosen' corner, placing him in the tray when he heads for the corner (he holds it) Nothing works and I've resorted to puppy pads in the corner which at least he goes on. I've protected the carpet under the pad with extra carpet.
Any other ideas?? The vet doesn't think there's much I can do. The only other thought I have is putting a bit off the soiled puppy pad in the litter tray or getting a hooded litter tray. It's so frustrating. He's a very clean and tidy cat, even wipes his paws before and after eating 
Thanks