We did.
Took on a cross of two working breeds who had spent the first 6 months of life living in a tower block flat, which she rarely left.
Young owner was a first time dog owner & fancied himself as a bit of a 'gangsta' & I suspect had done some amateur bite training ( the dog spent the first 2 weeks hanging off my arm and/or clothing) but apparently not any other sort of training, even house.
Dog was a bright, affectionate dog with us, but an utter monster around strangers, nervous of any new situations & couldn't be offlead so we spent a lot of time hiring enclosed fields to provide her with places she could run freely & unmuzzled.
We've rehabbed human aggro dogs in the past but this poor dog was wired wrong, backyard bred from some 'girlfriend's mother's auntie's postman' scenario.
People in the breed know they can be challenging, & often recommended aversives but I knew my dog, they would have suppressed her behaviour possibly, but her emotional state would have been one of even higher fear & anxiety.
We hired a good behaviourist & he did make some difference but she was still a risk, but we then had a management error & she bit a friend's arm, I wasn't there but my daughter said the dog just casually walked up to him, wagging her tail, & then grabbed him.
We talked to our vet at great length (vets were a challenge & she required sedation for even routine visits) & made the decision that her QOL was just not enough with how limited it had to be & no matter how well you manage things unless you're a hermit living in Fort Knox it's never infallible.
I was, & still am, devastated, still have nightmares & am saddened that 3 years of work couldn't fix her, because to me, in spite of her many issues, she was still a lovely dog.