Hi. I am 50 and have been using tret (0.021% with Skin & Me) for a good ten months and haven't really seen much difference. I am using it for anti-aging not for any other skin problem. Recently I have been getting a red and dry chin which is a bit grim and I think tret is the culprit. So if all tret is doing is making me look worse I am thinking of jacking it in. Has the anti-aging ship sailed??! Any advice appreciated.