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Tylenol / paracetamol and trigger for ASD?

11 replies

Clarissimo · 17/04/2010 13:58

Found an article Alternative from Medicine Review Volume 14, Number 4 2009suggesting this and wondered if anyone else had strong opinions?
abstract: 'Schultz et al (2008) raised the question whether regression into autism is triggered, not by the measles-mumps-rubella (MMR) vaccine, but by acetaminophen (Tyleno®) given for its fever and pain. Considerable evidence supports this contention, most notably the exponential rise in the incidence of autism since 1980, when acetaminophen began to replace aspirin for infants and young children. The impetus for this shift a Centers for Disease Control and Prevention warning that aspirin was associated with Reye's syndrome has since been compellingly debunked. If aspirin not to be feared as a cause of Reye's syndrome, and acetaminophen is to be feared as a cause of autism, can the autism epidemic be reversed by replacing acetaminophen with aspirin or other remedies? [ABSTRACT FROM AUTHOR]'

here

DS4 hs chickenpox atm and is doped up with calpol so guess thats why this stuck out but..... intreresting

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colabottles · 18/04/2010 13:08

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Clarissimo · 18/04/2010 14:13

The publsihed work is relatively recent though- and google-able so is it worth showing to GP?

We had to give ds4 calpol last night as he screamed for hours and it was more cruel not to (already ahd taken ibruprofen) but goodness I hated doing it

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asdx2 · 18/04/2010 15:28

Dd regressed spectacularly just after her first birthday. Lost all her skills couldn't even smile any longer. She was tested for Retts because of how suddenly it happened.
She was diagnosed at two with moderate to severe autism. She hadn't had MMR nor had she had calpol because she was the most ridiculously healthy child who never picked anything up and still doesn't.
Still hasn't ever had calpol because we have to use paracetamol suppositories because she won't take medicine.

Clarissimo · 18/04/2010 15:53

Its all paracetamool I think isn't it?

My take is that this if proven will still probably relate to a proportion fo ASD; increasingly iot seems to be an umbrella term for many disorders sharing core features. TBH, even my boys seem to be so very different so I don't think they have the same variant (well one has autism and ojne as dx) although of course it may be a genetic tendency triggerd by very different things IYSWIM. S3 had a bad fall not so long before his regression as well whilst even ds1's maternity notes mark him as independent!

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asdx2 · 18/04/2010 16:00

My two are total opposites too even though they have the same diagnosis. Ds never regressed but my concerns are mentioned from him being ten days old that something was wrong.Dd I thought was fine, and her being my fifth you would have thought I would have spotted something, until the sudden regression just after her first birthday.

Clarissimo · 18/04/2010 16:04

DS3's regression was just inside the 3 year cut off; until then he was incredibly palcid but verbal and developing in an NT way. It does worry me with ds4 that he could regress but all we can do is wait and see

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asdx2 · 18/04/2010 16:27

Did anything precede the regression? I have gone over and over the weeks leading up to dd's and I can't spot anything.
GP referred her to a paed immediately because she had seen her two days before when I went for my pill check. Dd was happy laughing and clapping, waved and said bye bye as we left.
Two days later she was making a whining noise, saw GP again who checked her over and she was fine with no sign of illness.
Two more days and the whining stopped and dd was without any skills and GP made urgent referral.
Can't think of anything out of the ordinary at all.

Clarissimo · 18/04/2010 19:00

MMR (late), a head injury, being prescribed a formula full of casein when i thought it was the casein free one he should have had (had it for 2 years)....

chickenpox aged 10 weeks with a bad reaction....

too many things tbh!

DS1 was a bad birth (eclampsia, distress but no anaesthetist available to help) but that was it. Lots of spectrummy people in the family though so IMO a definite genes plus environmental insult scenario

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asdx2 · 18/04/2010 19:35

You see I could see a hundred and one reasons for ds, whooping cough, anaphylactic shock, lots of antibiotics a fair share of calpol but he was odd from day one so preceded all of that.
Dd though had had no illnesses not even a snuffle so no medicines, no allergies, no MMR and it really was a bolt from the blue.
I suspect that the noise she made was cerebral irritation because it's a sound I had never heard before and haven't heard since but what caused it?
Funnily enough once she had lost her skills she started with allergies and eczema too although had none previously.

PipinJo · 18/04/2010 20:00

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Clarissimo · 18/04/2010 21:04

I think the calpol / paracetamol idea is that reducing a fever triggers an autoimmune response isnt it?

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