Can anyone help - coming off trimethiprim

[mummytopebs]

My dd 4 has been on trimethiprim for 3 years for recurrent infections, we try every may time to bring her off it to see if her immune system has strengthned any. Anyway she usually ends up straight back on it due to picking up infections. We took her off it 5 weeks ago and so far no infection (fingers crossed), however have noticed a real change in her behaviour, lots of tantrums, lashing out, her rituals have become more severe, she has no emotions towards others. The nursery where she has been really settled have noticed the change and she has been hitting out at children and staff - in short she has changed completely, brief history she is being assessed for aspergers or possible epilepsy or both, as well as having other medical probs.
Was just wondering if anyone has experience of this? The gp said today maybe the trimethiprim has been masking aspergers behaviour? Any advice appreciated cos her behaviour is terrible and i am at my wits end.

Anyone?

WHy are you taking her off it? Has the GP advised this?

I too my dd off it but very slowly, i.e. I gave it to her every other day for a few weeks, then every 3 days etc.

I also don't use any bath foam in her bath, only wash her hair in natural shampoo because it irritates her "down below". Plenty of baths in plain water to keep her bits clean.

I am very aware of her weeing and if I think she has the start of an infection I get her to drinks loads and have a long soak in the bath.
Hope that helps.

Her consultant says to try and bring her off it every year around this time, she was put on it for general infection really to try and stop her getting infections not just utis. She hasnt got a uti at the moment i am very concerned about her behaviour though

Hi mummytopebs, DS2 has trimethaprim and has had for about eighteen months, also for general infections but mainly resp and ear infections.

I'm afraid I can't help you with regard to behaviour but maybe an appointment with the consultant or immunologist may be in order. I'm not surprised your worried. Poor you.

We have been advised to keep ds on it for a good while yet as they are still fighting so many pre-school and primary school infections.

It may just be a coincedence I guess, has any other medication changed? Anything steroid based does very strange things to my son.

DD was on it for exactly the same mainly ear and uti but also for general infections. No other change in her medication, i am googling it now but so far come up with nothing re trimethprim possibly masking aspergers syndrome

I must admit, I read about side affects at the time he was prescribed it and didn't notice anything like that, but you never know do you, it could just be one ingredient that has made a difference.

Do you think you will be able to get an appointment to get her assesed again soon? Are you happy to have the trimethaprim stopped?

Oh my god slightly crumpled i know you shouldnt google but have found lots of stuff now about a research done in 2002 into it affecting your brain!

My daughter has been on a nighttime dose of 7.5ml for 5 months for a sinus infection. She sees the ENT consultant tomorrow and I hope he will say she can stop.

Oh no really! Do not google anymore my love. Print out what you have found and take it to your doctor/ consultant. I know you know this but remember google is not an acurate source of info. Don't panic.

What dose does she have? I would imagine you would have to have a lot for it to have any kind of affect, although their bodies are so small.

I would love for ds2 to stop taking it but his reality will be so many infections. We know he has a comprimised immune system, lesser of two evils I suppose. Mind you if the research is correct I shall be asking for something else for him.

She has been on it for 3 years for the same a comprimised immune system and the dose goes up with her weight she started off on 1.5 ml and is now up to 2.5 ml, i am not disputing it has been a godsend to us but needless to say i am a bit worried about the change in her behaviour. I have been to gp this afternoon and they are hurrying up her referral to child pyscologist, so surely they would know??

slightly crumpled what about asking about aazithromax dd has is for comprmised immune system