Strong genetic link in my family, DS is diagnosed HFA (I probably have it too and other family members most likely to have aspergers or HFA, including one case of diagnosed classic autism.
DD is now seven, was a hellish baby, screamed for 3 months. Ok as a toddler (but absolutely no separation anxiety whatsoever, happy to play on her own for the entire day, never minded being left. Always very fussy about seems, and textures.
Started school, very advanced academically in all areas except hand writing, struggles socially (never invited to playdates) although some of that may be my fault! Always wants to be in charge and lead everything. Gets on well with older children and adults. Very pedantic, uses very advanced words (more like an adult)
She is also hypermobile.
Not interested in toys, watches Harry Potter over and over again, or plays on the computer. Likes mixing up potions (ie water and flour and leftover kitchen stuff)
Takes 2 - 3 hours to fall asleep every night (like her brother)
I did mention my concerns to the school, but they dismissed it, as she is doing well academically