Not a good combination, imo.
The only two that hang well together are Maths and business studies, though the latter isn't really regarded as a rigorous subject by many universities.
Depends on what he wants to do afterwards really.
If he wants to do something theatre-related, then he'd be better off with English to go with it.
If he wants to do something mathematical, then he should do another maths-based subject eg. further maths, physics, or even economics.
To do anything with his biology he should do chemistry alongside it.
I hear what you are all saying about breadth, but there is a difference between breadth and incoherence, and the subject combination outlined int he OP is the latter. FWIW my dd was wondering whether to do Biology alongside her three arts A-levels to give the impression of breadth, and she was advised against it. Several teachers said that hte students who really struggle at Biology AS level are the ones who are doing it as a lone science subject, because it is such a very different skill set from the arts subjects, and also because they lack the input from doing chemistry alongside.
If there is a possibility that he might want to do serious academic subject at university, then he should rethink his options. And the school should be telling him this, tbh.