It is definitely possible yes.
I think -
Ask yourself what is causing your low self esteem? Childhood? Life experiences? Thoughts patterns? Something tangible - 'when I XXX, I know it's wrong and then I feel bad about myself.'
Take it from there.
I had low set esteem due to an abusive childhood. I learned all about how the child ego forms, how important love is from caregivers, what happens when there is no love, the child doesn't know itself as good, as enough, as worthy of love - yet if you had given that same child to a couple who had wanted her or him and had loved her or him, that child would know itself to be worthy of love as it would have grown up knowing that, even when it made a mistake or did wrong, it was basically loved.
From there, I asked myself, how do I know I have low self esteem? is it my thoughts (I'll never be like them so I won't even try.) Is it my behaviour (I won't go for that, I'd never get it.) Is it how I speak about myself in public (Thanks for putting up with me.)
This then needs to be addressed, on a daily basis - and not in a trite manner. I had to practice not saying bad things about myself, I had to challenge not wearing things I liked or drawing attention to myself, or thinking I'd never fit in or no one would want me. Why would that be true? Because of my mother drowning me and saying she hated me? I had to join the dots and then work my way out of the habits that kept me down.
I used self help books and journalling - it took a long time - my PMT helped me by showing me what wasn't working - but in essence, I fully believe you can sort out low self esteem.