Op, I think it is the quality of friendships that make the difference here.
I'm sorry for the loss of your mum, it sounds like you had a lovely relationship there, someone to listen and I realise the value of this as I get older.
I have a good friend but lately it doesn't feel like she is listening properly. She doesn't check in with as often as she could (very little) and it is me who contacts her to chat. In essence, I am not a priority to her and she is becoming less of a priority to me. I realise I need different friendships, I'm working on it but it can be difficult as really good friends can be difficult to find (the meet up every few week friends much easier to find). I am on the waiting list for counselling as I feel a real gap here - I would really value someone who would just sit and listen. It shouldn't be much for us to ask for really but for some of us it just turns out this way.
How is it that you only see your boyfriend once a week? This doesn't sound like it would help emotional connection.
Working from home won't help either most likely as it doesn't bring you into contact with people in 'real life'. You have a number of things going on here - loss of your mum, limited time spent with your boyfriend, less contact with your children and working from home. I can understand why you might feel the need for more human contact.
I have a lot of limitations (won't go into them here) but essentially, I could become lonely. Fortunately, I have interests that keep me connected with self also. Having said this, you can't beat the human connection and interactions.
Not sure what to suggest op, other than perhaps a change of job. Hopefully, someone will come along shortly with other suggestions. There is always the obvious - investigate your interests etc. as this might widen your potential for meeting others (it is through this that I am slowly building a social network). I feel for you as nothing is an instant fix in terms of forming human relations.