Same boat here. DH been on meds around 2.5 years, has bipolar 2 with a lot of depression and anxiety. Gave up his self employed job last summer and has been on ESA since. Spent the last year moping around the house and not doing any of the self care (exercise, routine, eating well, etc) that he knows would help. He's on medication, but it's been changed countless times and doesn't seem to do much except sedate him so he feels even less like doing stuff.
I have been financially, practically and emotionally supporting our family (3 DCs) for so long and feel like I am on the verge of burnout/depression myself. But I can't moan or do anything about it because he's not well. It's shit and I don't really see it getting any better...
DH has noticed I've been distant recently and we had a bit of a chat the other day about how I feel a lot of pressure and resentment, and sometimes struggle to be 'nice happy wife'. Nothing changes though, I just carry around all this anger and resentment and sadness, on top of worrying about money because I'm trying to support us on one wage. He's on a scheme to retrain in a new career which he is pinning all his hopes on, but it's currently being held up and instead of using the time to do some of the many things he needs to get done, he is spending his days on the sofa. Apparently he will be magically fine the minute he gets a call to attend his training...
Wow, sorry, long post. But OP you are not alone, many of us out here!