We have done this for many years. Being apart regularly isn't ideal but it does have some unexpected up-sides.
Faced with it or moving children out of school every year, we decided to make the most of having to be apart some of the time and use it to keep things exciting.
When it began to be a regular thing, the children were 2 and 4. I stayed at home with them and DH worked away during the week.
The pattern for us is that we would work hard to do all the chores/homework/appointments during the week. I kept the children really occupied and myself busy. We talked/skyped each night - and made things 'for dad'.
Then on Friday night every week it would be party night - everyone's favourite food/(loud)music -and we had fun. For me and DH it would be romantic too - dressing up a bit and really enjoying being together. Missing each other makes all the little irritating faults much less noticable.
This has continued into teens/twenties for the children and it still works.
We still really celebrate being back together. These days the DC's come back home from their grown-up lives and expect the same celebration on their arrival.
This is a life of intensity! Priorities are different. Weekend days together are really treasured - every minute counts - even doing ordinary things.