There are a lot of good points made there. I really appreciate all your comments. I am on my phone so I can't see them while I write this but picking up on a few points.....
I definitely feel like I want to get out of the house and do my own thing more often. A new job would be great, when my DH was diagnosed all those years ago, I was in the early stages of setting up my own business with a friend but totally lack confidence in doing such a thing now as it has been so long, I feel I need to retrain.
I would love to take on the challenge of something new but it's hard to know which direction to go, I think when you are younger you have chance to change direction but I feel that I would need to be going in the direction this time as it may be the last chance to get a good career built.
I know I need space from the children, give me some sanity back, I feel awfully guilty though. I have looked at nurseries but because DS1 and DD1 didn't go, I feel awful about putting DS2 in. :-/
As someone said, my life doesn't sound perfect, people think I have a great life as I have the big house, lovely car, successful business, loving husband and gorgeous healthy children. It all 'looks' perfect, but yes, I am bored silly and yes, probably not depressed but certainly a bit down.