Haven't RTFT, but for what it's worth:
We moved to Devon (2.5 hours away from family) with one toddler 20 years ago. We had an absolute dream house, dd1 and later dd2 had a fab childhood and I never felt a moment's regret about the move. Loved it, made good friends, settled well, made an effort to go back to see everyone plenty. My parents were able to come down a few times a year as well.
I still don't regret it, I still feel their childhood was awesome here.
BUT. I do now feel guilty nonetheless. We were 25 mins minimum drive from everyone when we lived up there, so we all had separate lives in terms of day to day schools/communities, but we were all within popping in/day trip distance. Now, dd20 is at uni, dd16 is at 6th form, I'm (still) flat out working FT, now divorced, remarried, etc etc. Life moves on and everyone's needs change.
I still make huge efforts to visit my parents every 6 weeks minimum but they've seen FAR less of the kids than they would if we hadn't moved, and they are now old and frail themselves.
The kids when little were easy to load in the car and take to family for weekends/part of school hols. Once they had their own lives, much as they still enjoy seeing family it became way more difficult. Not to mention the cost of fuel, having to be away for a couple of days as a rule to spend enough time with people, animal sitting etc. For a long time I tended to visit with the kids and ex h tended to stay home, working and looking after animals.
Fast forward: my dad is now disabled following a stroke and cancer over the past few years and my mum is struggling to care for him. They couldn't cope with moving now, and in any case my only sibling is 2.5 hours in the other direction so they'd feel they were abandoning one of us whichever way they moved. They also have good friends and extended family in their area, and thankfully enough money to pay for gardening and cleaning help.
These days I feel constantly torn about being unable to just pop by and help with minor things. When we decided to move, I didn't think beyond having youngish kids and it being easy enough to nip back in a couple of hours if we were needed. It's hard, but I don't think in all honesty I'd change the decision we made. I do believe it's been best for the kids.
Just some stuff to bear in mind for when a few years have passed. Best of luck whatever you decide.