Honestly Saltaire is brilliant. It's really the best of all worlds with a villagey feel, loads to do and great community. We moved over here from Leeds 5 years ago and I don't miss Leeds at all. And because it's a Bradford postcode, you get a lot more for your money than in Leeds. Saltaire village is a conservation area and so the houses are grade 2 listed, but adjacent to the village are lots of really nice streets of big Victorian terraces and in the Nab Wood/ Moorhead area where we leave, you can get nice 1930s houses with decent gardens.
I wouldn't be put off by the proximity to Bradford, yes there are areas that are deprived and not great, but no worse than bad areas of Leeds or any other big city. Heaton, the nearest suburb to Saltaire is absolutely fine. The main annoyances are the volume of traffic but we've found the area very safe and had no issues in 5 years.
Also, if you are planning to TTC soon, Saltaire is in the catchment area for Airedale hospital, my wife unfortunately had a miscarriage recently but the level of medical care and aftercare she received has been outstanding, so if you moved to the area and booked in there, you'd be in very safe hands.
We've not had any issues with noise from the flight path. I'd say you'd have a lot more issues with this in areas like Horsforth and Otley (although these are both very nice areas too!) the drawback to Otley is no train station, but it's closer to Leeds and has very good access to north Yorkshire. Ilkley has a station, but as you say, property is a lot more expensive as it's very desirable.
Good luck with your search!