In a nutshell yes.
Particularly 30-45yr old couples with established careers & children, who don't really get much out of the London 'buzz' like they did in their 20's, & are essentially still there, compromising their life living in an overpriced terrace without a garden in Z3/4, because of employment.
It's always been common for those in that position to move to the outer zones or commuter towns in search of a better compromise; more space etc.
Covid/WFH has rapidly tipped the balance severely in favour of such a move for a large number of people, & also removed much of the incentive of that 'first step' expensive house in the nice areas of Z3/4.
A big commute sucks when you have to do it 5 days a week to a regimented 9-5.
When you only do it 1-2 times per week on flexi hours, it doesn't.
Yes, some will be returning to the office full time, but lots won't be.
Areas most likely to be impacted? The fashionable/expensive family friendly enclaves of the ordinary professional - nappy valley etc, IMO.