Pack as much as possible ahead of time, and stack it for ease of transport - so if you can, pack up boxes and stack in a spare room now, but move downstairs to living room the night before.
Things like books, music, ornaments, summer clothes (if moving in winter), "good" dinner service or kitchen items not often needed (turkey plate, kenwood chef used rarely etc), that sort of thing are all good for early packing. Emptying out cupboards and drawers so that furniture is empty and ready to move is also really good.
Try to get started early, and to declutter as you pack. So things go to the charity shop, recycling bin or dump before having to be transported to the new place.
On the day, put a suitcase with a change of clothes for the household, PJs, washbags, etc all together and put that in the car. A second suitcase/black sack should have sheets, duvets, pillows and a couple of towels. Also, put the kettle, mugs, box teabags, jar coffee, bag sugar, teaspoons, 2 packets biscuits and a bottle of milk, along with cleaning items (clothes, spray, couple of pairs of gloves, roll of black sacks, washup liquid, liquid soap and a couple of teatowels and handtowels), roll of kitchen towel and a 4 pack of toilet roll - into a box/bag - these also go in the car. They are the first things to go into the new house (whether using a "man with a van" service or lots of cars yourselves). So the early arrivals can do any cleaning needed, have the kettle hot as people need a cup in their hand, and can start on making up beds as soon as the actual beds arrive. (Essential kitchen items for the day, a few tools like screwdriver and hammer etc are also useful, and maybe some tape, nails, screws, cuphooks etc - depends on how organized you are and how much you think you might need that day).
Do you have anyone who can take the DCs/dogs for moving day? Particularly the dog, and the DC depends on their age and likely helpfulness (anything under 5 definitely ask for babysitter, over 5 consider the individual DCs and ability to help and not hinder).
It's perfectly do-able. DH and I did it (before DD but in 1 day and having no family available to help on the day so used a removal service). And I have been involved in helping a DUncle do it 3 times, all in 1 day and he had a LOT of stuff every time, even the times he had a truck it needed multiple car journeys ferrying as well.
LABEL EVERY BOX - Room to go to, and an idea of contents. Have a master list (preferably in a notebook) of all boxes and their main contents, and put a list of all contents on a loose leaf sheet of paper in the top of each box before taping it up. Makes it a lot easier to find the corkscrew late on night 1 or the whisk after 5 days of chaos.
If you DO have helpers, get 1 to stay in the new house after the first run. Their job is to get the kitchen functional - kettle etc for cups of tea first, then clean a bathroom for use on the day. After that, it depends on what boxes and furniture have arrived, but the 2 main priorities are to get beds up and made, and to get the rest of the kitchen somewhat sorted (putting crockery and food away etc, and filling the fridge with whatever comes from the old fridge in a freezer bag or from the shops). They continue emptying the priority boxes as they arrive, in between looking after other helpers arriving and leaving - they are also present as security so that only people involved are in and not anyone chancing their arm and walking back out with boxes.
HTH