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Pregnancy

Talk about every stage of pregnancy, from early symptoms to preparing for birth.

5wks pregnant & taking heparin, aspirin and progesterone. Anyone else?

15 replies

peepee · 17/08/2005 11:30

Hi,

Just looking for some support and advice on any others who have been prescribed any of the above for thinning out blood during pregnancy.

I have had 4 m/c and 0 viable pregnancies. I am being monitored at Queen Charlottes in London. Prof. Bennett is my consultant.

Have had loads of blood tests and scans which show all is in order. Had a scan yesterday but all they could see was a black blob. Have to have another scan in 2 weeks to check on the baby.
I am quite anxious but feel happy that someone is taking care of me and trying to help.

There must be more of us out there.

Please check in for chats.

PeePee.

OP posts:
bonkerz · 17/08/2005 11:32

hi peepee, i had 2 mc and when i got pregnant this tiome the doc put me on aspirin as a precautionary measure. We will never really know if this helped or not but i am currently 21 weeks pregnant and after 6 scans and 2 small bleeds all is brilliant. Goodluck.

RedZuleika · 17/08/2005 14:06

Hello.

I'm on heparin and aspirin until next week, week 36. Three previous miscarriages. Blood tests early in this pregnancy indicated raised anticardiolipin antibodies. I have lots of information on antiphospholipid antibody syndrome and I know what the RCOG indicates is supposed to happen under this drug regime - but I was assumed to be telepathic and have had no monitoring through the NHS, other than three scans between weeks 6 and 11. I do have an independent midwife, so have been fairly confident on the growth rate, however.

Interestingly, having done some research and gone back to my GP and consultant, somehow their first reaction is to blame me for not getting monitored...

How far along are you? And can I ask for what condition they've prescribed anticoagulants?

There are more of us out here, but not that many I've discovered...

RedZuleika · 17/08/2005 14:09

Sorry - just realised you've said how far along you are...

There's a lot of conflicting advice surrounding the drug regime, I think: I've read and been told that one should take the aspirin from getting a positive pregnancy test and the heparin from week six - but obviously your consultant has put you on the latter before this.

Charlee · 17/08/2005 14:39

I had some major blood clots on my lungs whilst pg with DS and now have to take Clexain injections which is a form of heperin everytime i have another baby, but i havent had your exact expericence, i was monitored and scaned weekly whils having ds though, so its good there looking out for you early as mine wasnt discovered untill i was 20 weeks and was rushed into hospital with breathing difficultys.
DS is now 11 months and doing fantastic, he is quite small but i dont know if that has any relevence.
I have had m/c's but again i dont know if there a link.
Good luck x

peepee · 17/08/2005 19:29

Thanks for your responses. I am glad they are positive ones.

I had blood tests done about 3 mths ago and this indicated that there was no problem other than the fact that my blood was a factor 8 (?) when i asked the prof to explain all he could tell me was that my blood was thick and this could be a reason why I kept miscarrying quite early on. Though I said I was taking heparin it is actually called Clexane. From what I can make out it is slightly milder than heparin.

I have a close freind of mine who had the same problem and was only prescribed aspirin. It worked. I wonder why i have to take the two? I suppose i shoul've asked but i was so releived that they were giving me something straight away.

Anyway, have done two jabs so far. They don't really hurt, it's just that I keep getting bruised. I am injecting in my upper thigh. Is it easier in the side of the abdomen?

Am going on a cruise in 3 weeks (transatlantic) and was really looking forward to it until this. I am going to be covered in bruises. Won't be able to drink nor have much of the lush food! Never mind, I will try and enjoy it.

Thanks again for the responses.

OP posts:
RedZuleika · 17/08/2005 20:41

Clexane is what I'm taking too - I think it's low molecular weight heparin, isn't it? - doesn't cross the placenta.

The instructions in the packet say to do the injections into a pinch of flesh around your abdomen, but I always do mine in a stretch of fleshy bit at the top of my thighs. For some reason, there's a patch on each leg where it doesn't hurt. When the nurse showed me how to do it, she rubbed it afterwards and caused a massive bruise. I've since discovered that following the packet instruction NOT to rub means that there's hardly any bruising.

One thing worth bearing in mind - if you're flying at any point as part of this holiday - is that you'll need a letter from your doctor indicating medical necessity if you want to take syringes in your cabin baggage. And I personally would always opt to take them in my cabin baggage, rather than put them in the hold, having seen people loose their medication that way and things go pear-shaped.

I don't know about your condition, but I know with antiphospholipid antibody syndrome that some success is achieved with aspirin, but a higher success rate is achieved with an aspirin / heparin combination. I think they work on the clottiness in two different ways.

How does everyone manage for sharps bins?? They're like gold dust round here...

peepee · 18/08/2005 21:53

My hospital gave me a sharps bin.

Thanks for the advice about flying. Though we start the cruise in Southampton it ends in New York and that means flying home. I will take a letter just incase.

I tried injecting myself in the abdomen today. As I have to do it at 0800 every day I had to take it to work with me as i start at 0700. I messed up. Instead of jabbing into fat (and I have loads of it) I jabbed just under the skin and syringed in the clexan. I thought i was going to faint! The injected sight bubbled up and left a lump. I realised what was happening and stopped. I then syringed the rest of it into my thigh. I am just going to alternate legs from now on. I was all alone and so freaked out by wot happened. I can't beleive i have 2 do this 4 34 wks!

Hope this works.

Redzulieka, are you taking progesterone too?

OP posts:
peepee · 20/08/2005 13:21

Is anyone taking the progesterone supositories?

What are the effects? Any odd discharge?
Sorry to be so graphic but just making sure it's not just me!

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Bumpyroad · 20/08/2005 15:12

I wish you every success! It sounds as though you are in good hands. I can't imagine the daily injections but I know that I would be willing to do the same to have another baby.

Quick question for Bonkerz if I may: How may MG of aspirin do you take in a day? Does it matter what time of day? I am nearly 11 weeks and my gp knows nothing about the aspirin option (have had previous miscarriages) although it was suggested to me by a consultant following my last evacuation. I would love to feel like I am doing something to prevent another loss.

peepee · 21/08/2005 07:47

Bumpyroad,

Everyone I know who is and has taken aspirin take 75mg daily. I try to take mine at the same time daily but I don't think it matters. The heparin has to be taken at the same time and progesterone b 4 bed for obvious reasons.
Your GP has to give you a perscription for the 75mg of aspirin, as you cannot buy them over the counter. Over the counter one's are about 300mg.

Take care

Peepee...

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RedZuleika · 21/08/2005 21:27

I'm taking 75mg aspirin a day too. To be honest, I'm not that careful about taking either the heparin or the aspirin at the same time each day, just as long as it's in the same ballpark. I always do the heparin after a shower / bath, otherwise the injection site bleeds.

You can buy 75mg over the counter. I just went to Boots and asked for baby aspirin.

I quite often get the bubbling thing going on, even in my leg. I'm not sure that I get it particularly because I've injected in at the wrong angle or not deep enough or something. One thing I have noticed (after injecting for 30 weeks) is the variable quality of the syringes. Quite a few have bent needles, are difficult to depress or the double sheath separates when I try to open them. Ok - so you can bend the needle back and the difficulty in depressing them isn't the end of the world... but I can't help feeling that the way the double plastic sheath sometimes separates makes it more likely that someone will stick it in themselves before using it. Obviously, this doesn't matter if you're just doing it to yourself, but I wonder about a third party doing it.

I'm not taking progesterone, btw. But I thought odd discharge was part and parcel of pregnancy...

RedZuleika · 21/08/2005 21:31

Peepee: not to be a worry wart, but I would make sure the doctor / receptionist knows that you need a letter outlining medical necessity, NOT a 'fitness to fly' certificate or the such like. I know someone who left it a bit late collecting the letter and the doctor had done the wrong one. I guess if you're looking at carrying syringes on the return journey, it's not as imperative as on the outward, though.

peepee · 22/08/2005 10:07

RedZuleika,

Thanks for your advice. It has been very helpful. I will call my GP today. Mind u, I have not eveen informed them of the pregnancy.

You must be very excited only having a few weeks left. I really do hope and pray that one day I will be at your stage and advising someone like me.

Am feeling quite light headed today. Have been getting really bad heart burn and a nauseous feeling. Can't complain though. The more discomfort the better.....So I have been told!

Have got the decorator in at the moment. He has been here since 0745. I really can't wait for him to finish and go. I heard him on the phone about 30mins ago saying he would be finished in about 2 hours. Great......I will have a snooze before getting to work for 3ish.

I have been in bed most evening by 8ish. I am working tonight until 10. How will I cope??? DH thinks it's quite funny. So do I really. I will just recline my chair and fall asleep.

Perhaps I will just go on line and catch up on some of the other threads!

Peepee.

OP posts:
RedZuleika · 31/08/2005 16:55

Hello. I've been meaning to come back to this thread for days, but frankly I've been too exhausted. (Too exhausted to be excited actually...)

Peepee: I don't know anything about your condition and I'm not doubting the integrity of your consultant, but based on my own experience I would try and find out as much about the condition as you can. I only say this because of the amount of rubbish and conflicting opinions I've been given recently.

I saw a different consultant a couple of weeks ago - but only because there were no ultrasound appointments available in three hospitals and she was the only person who could do it. I initially thought she was nice enough, but the more I think about it, the more I realise how manipulative she was. She asked me if anyone had discussed the risks of a home birth with me, given my 'high risk' status - and said that people with antiphospholipid antibodies are usually induced between 38 and 40 weeks - and definitely by 40 weeks. She then said that I was at higher risk of pph (eh?? aren't I a clotter not a bleeder???) and the peanut of intrauterine death. We asked her what the statistics are on this, but she couldn't provide any - but then went on to say 'Of course, this IS your FOURTH pregnancy...' and 'It is a PLANNED pregnancy...' What the hell difference does that make? I'm not sure that someone who has never had a miscarriage, or has reached this point in an UNplanned pregnancy would sit around thinking 'Never mind, I'll just let it die, I can always make another...' if there were strong evidence to suggest induction at a certain point, due to placental insufficiency.

This consultant had the cheek to say that - whilst I couldn't use a birth centre (tell me something I don't know...) - I could have a 'low intervention' birth on the main ward and I didn't have to have an epidural. Thanks a lot. How they expect someone to labour effectively without painkillers when they've barred other methods of 'natural' pain relief (eg birthing pool), I really don't know. Not to mention the fact that epidurals are contraindicated when you've been on heparin due to the risk of bleeding into the spine.

Besides, as I keep ranting on in various places on MN - part of my thinking in trying to have as active a birth as possible, and trying to reduce my chances of a Caesarean, is that by keeping mobile, I reduce my risk of dvt.

Anyway - I was fairly upset by this whole conversation, but my gut feeling was that in the absence of firm information, I would decline induction before my due date - and base my decision thereafter on facts presented to me. We asked this consultant for facts relating to intrauterine death with my condition, but she couldn't find any to hand, said she would look on the internet (like I can't do that myself?) and give them to the midwife present, who would be at the ante-natal clinic at which I had my next appointment this week. Needless to say, they didn't materialise.

Despite this consultant going on about how it was my decision etc etc, she'd written across the scan report 'Recommend IOL by 40/40, discuss with Mr X'. Amusingly, when my consultant saw this, he went off on one about how he'd only sent me to her because she had a skill that he needed to use and if he'd wanted an opinion, he'd have asked for it (the implication being that it will be a very long time indeed before HE goes to HER for advice...) and if she's going to make comments like that, she should really have all the information and statistics at her fingertips.

He also completely slated the advice given to me by his registrar a few weeks previously about when I should finish the anticoagulants (now extended to the beginning of labour, recommencing afterwards for six weeks), saying that he doesn't hire these people, he has no control over them and that this particular registrar should know better.

He also confirmed that I could have a natural or managed third stage, if I wanted, and there are no implications thereto with the antiphospholipid thing because I AM a clotter, not a bleeder. Which also means that the consultant who did the scan was also talking rubbish.

He doesn't approve of the home birth plan - but then I never expected him to - but restricted his comments to a statement of fact and three lines in my notes. Bless him. His concern with regard to myself is that I apparently need to be monitored for clots. How they would intend to do this in hospital without comprising my movement and therefore making clotting more likely, isn't clear to me...

I do feel a certain pressure, that because this person has diagnosed a medical condition and I'm now 37 weeks pregnant because of that, that I should follow ALL of his advice, or else I'm being ungrateful... which is silly really - because it's still my body and I'm still entitled to make informed choices.

Anyway - that's my twopennorth for the day...

RedZuleika · 31/08/2005 16:56

Incidentally, the design of the sheath has been changed in my most recent batch of Clexane - so I can't be the only person who's had reservations about them.

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