With my first pregnancy, I had SPD from about 24 weeks. Now I am 8 weeks pregnant with twins after IVF, and my clinic has suggested that I continue taking progesterone gel till 90 days (as is routine in their protocol). But the last few days I have been getting SPD symptoms, with the pain so severe last night that I just couldn't sleep. This is quite scary with the thought that I have 32 weeks to go! I've found online that progesterone is a muscle/ligament relaxer, and I wonder if the progesterone is contributing to this early onset? Also, I've heard some clinics don't prescribe progesterone for as long as 90 days. Does anyone have any experience? I am considering coming off the progesterone in the hope it will lessen the pain. Any advice appreciated.