I found a few things about it harder, but mostly it was much easier than going from none to one (for me).
Things that were hard at first:
Going out with a walking toddler and a buggy. I did it as little as possible, though. used a sling for the first few months and did my food shopping online - little shortcuts like that.
Jealousy from my older child. He would 'play up' the minute I sat down to breastfeed or picked the baby up to comfort her. This has been a biggie, actually, and is only really calming down a year on.
Not having the endless time you have after your first baby to mooch around breastfeeding and snoozing when your baby does. Forget about it!
However, I found going from no children to one so extremely tough, that nothing could be quite as hard as that again. I just felt much better prepared second time around and a lot more relaxed. I didn't know I'd feel more relaxed (wasnt feeling especially chilled out while pregnant) but as soon as my second was born I realised I just felt much calmer and more in control. I didn't freak out about stuff.
Anyway, that was my little waffle about how it was for me.
Good luck. You'll be fine.xx