Just posting this because it may be of interest to others.
We had the combined test at 12 weeks which was bloods plus nuchal scan. Combined with my age (38) the result was 1 in 86 due to a low PAPP-A result.
We were a bit wobbled by this but weren't interested in CVS as the risk of miscarriage was higher than risk that baby had an abnormality. But we did feel it was a low result that we wanted to understand better.
I did a lot of research and decided to go for an integrated test privately as it is supposed to be more reliable. Then I did some MORE research and read that scanning for things like the nasal bone and other markers is a very thorough and reliable way of screening at 12 weeks. So we went to the Fetal Medicine Centre for a more comprehensive scan.
Based on the FMC result my risk dropped to less than 1 in 1600.
Today I got the result from my integrated test and it's 1 in 370.
By the way if I'd known about the nasal bone scan etc I wouldn't have done the integrated, but here we are and I just thought it was interesting to show others how different the results were.
We won't do any invasive tests. I'm happy that my risk is low and anyway I'm not sure I would do anything about it now even if it was high. But it's raised some questions for me about the whole screening process.