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Pregnancy

Talk about every stage of pregnancy, from early symptoms to preparing for birth.

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MNHQ: Paracetamol and pregnancy: what you need to know

9 replies

BeckyAMumsnet · 23/09/2025 17:49

Hi all,

We’ve seen many questions and concerns on the boards today following the recent comments from President Trump about whether taking paracetamol during pregnancy could be linked to autism. We were contacted by the Department of Health with some information that we hope will help reassure you.

A new, large-scale study has looked into this, and the results are clear: there is no evidence that paracetamol use in pregnancy causes autism in children.

The key findings:

  • A 2024 study from Sweden followed 2.4 million children, making it the largest to date on this topic.
  • Researchers compared siblings where one pregnancy involved paracetamol use and another didn’t, and found no evidence of a link between paracetamol in pregnancy and autism.
  • Untreated pain and fever in pregnancy can themselves pose risks to the baby, so it’s important to manage these symptoms safely.
  • Paracetamol remains the recommended pain relief in pregnancy when used as directed.
  • Alternatives like ibuprofen and other NSAIDs are generally not advised during pregnancy.

Dr Alison Cave, Chief Safety Officer at the MHRA, said:
“There is no evidence that taking paracetamol during pregnancy causes autism in children. Paracetamol remains the recommended pain relief option for pregnant women when used as directed. Pregnant women should continue to follow NHS guidance and speak to their healthcare professional if they have any concerns.”

You can read more on the NHS website about medicines in pregnancy, and report any suspected side effects via the Yellow Card scheme.

MNHQ

nhs.uk

Pregnancy, breastfeeding and fertility while taking paracetamol for adults

NHS medicines information on paracetamol and whether you can take it while pregnant or breastfeeding.

https://www.nhs.uk/medicines/paracetamol-for-adults/pregnancy-breastfeeding-and-fertility-while-taking-paracetamol-for-adults/

OP posts:
Mwnci123 · 23/09/2025 18:29

Thank you

NotEnoughKnittingTime · 23/09/2025 18:30

Autism has existed before paracetamol. Enough said. 🤷

ProfoundlyPeculiarAndWeird · 23/09/2025 21:00

Just bumping these sensible words.

KelsCommemorativeSausage · 23/09/2025 21:01

Thank you!

PermanentTemporary · 23/09/2025 21:04

Thank you @BeckyAMumset and MNHQ for taking responsible action to spread the word.

JadziaD · 23/09/2025 21:34

Nicely done

NeuralNurture · 24/09/2025 11:59

Is this the referenced study?
https://pubmed.ncbi.nlm.nih.gov/38592388/

Acetaminophen (paracetamol) depletes glutathione, the liver’s main antioxidant and detoxifying molecule. So any use of this drug carries a risk because harmful substances will be present in your body for longer or at higher levels than if it was completed avoided.

Avoiding it completely in pregnancy is a good idea. Along with avoiding many chemicals, dyes, and other pharmaceutical products as much as you can.

Autism is likely caused by many factors, genetic ones are not acting alone, there can still be dozens of environmental factors that increase the chance of developing autism to different severities, depending on your genetic predisposition.

Here is an example of a paper that does happen to find an effect:
https://pubmed.ncbi.nlm.nih.gov/26688372/

Dr Alison Cave’s quote in the OP is inaccurate, as there are studies that show an effect. Her quote, in her position, is a result of corporate capture of the MHRA regulatory body.
Regulatory bodies such as the FDA/WHO/MHRA receive money from industry, it’s called corporate capture. The studies that are funded by industry are designed in such a way that makes it likely they will get the results they want so they can continue to sell their products.

The study included mothers of all ages, as we age our livers become less efficient, so likely the risks of using paracetamol in pregnancy might increase with maternal age. Just as you can design a study that shows there is very little to no observable statistical risk, you can design a study that does show there is an effect! As an example you could try to find an observable effect by studying older mothers who only used paracetamol multiple times in the first trimester...

All drugs pose a risk, nothing is 100% safe. Trusting in our regulatory bodies, and in single research studies might not give us the best chance at a healthy life.

I personally, would not reach for a fluorescent yellow Lemsip, or paracetamol tablet for a cold or a mild-headache at any time. High fever in pregnancy is more complicated, and I hope that the government fights the corruption in our regulatory bodies so that we can start to rely on quality scientific papers to inform ourselves.

Good luck to all mums trying to make good decisions for themselves and their children in our modern world, which is rife with corruption and harmful environmental substances and products.

Maternal use of acetaminophen during pregnancy and risk of autism spectrum disorders in childhood: A Danish national birth cohort study - PubMed

Acetaminophen (paracetamol) is the most commonly used pain and fever medication during pregnancy. Previously, a positive ecological correlation between acetaminophen use and autism spectrum disorders (ASD) has been reported but evidence from larger stu...

https://pubmed.ncbi.nlm.nih.gov/26688372/

BIWI · 24/09/2025 12:10

Interesting post (and poster - check out the spelling of the username) which isn’t an official MNHQ post.

BeckyAMumsnet · 24/09/2025 12:42

Hi @BIWI it is me, sorry, Have corrected.

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