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Pregnancy

Talk about every stage of pregnancy, from early symptoms to preparing for birth.

Pregnancy mid 40s (pros + cons)

30 replies

Sunnyperfume · 18/08/2025 21:00

Not pregnant yet but thinking of trying for another. Currently just turned 45 so if all goes well I would be having baby at 46 years old. I'm aware of the possible issues with conceving, etc but I'm looking at the pros and cons of actually having a baby at that age. Does age affect the baby (during pregnancy or once born)? Do the scans usually pick up on all the issues that can occur? Does a baby in mid 40s impact your relationship with your partner? I know having a baby is always lovely but, realistically, would it be too much mid 40s?

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curliegirlie · 19/08/2025 16:56

The scary numbers are not a given. I’m 43, currently 17 weeks, my NIPT came back as low chance for all trisomies, and my combined test came back as 1 in 2400 for Down’s syndrome. This is despite my age and my eldest daughter having Down’s syndrome (I was 32 when she was conceived).

That said, this TTC journey has taken 3 years, with 2 early MCs and a CP along the way….

StandFirm · 20/08/2025 17:10

In my experience, it's not as straight forward as a pregnancy when younger but conceiving is certainly not impossible. I had a surprise pregnancy last month (I am 45 too) and sadly just miscarried. It's always heartbreaking regardless of age. Now I've had two MCs it's become more unlikely I'd have a successful pregnancy going forward but H and I were willing to go for it had it been viable. I'd booked early testing (NIPT) and would have had to have been monitored more closely. I was also honestly worried about the health risks to myself and what would happen to my other DCs in case something bad happened. Even though I wanted to keep it, I personally won't try again because this pregnancy and MC have been so very stressful, exhausting and painful even though it was still early (7.5 weeks). I am now grieving the fact that my childbearing years are finally over because I don't feel I want to take those risks again- but no medical professional has told me it would be impossible should I want to give it another go. You will have to gauge the risks for yourself taking into considerations your health and other circumstances.

curliegirlie · 21/08/2025 12:53

Exactly, your own health is so personal to you. There’s no age related one size fits all scenario. This pregnancy at 42/43 has been very easy so far - no nausea, no infections, all tests have come back fine. I had my 16 week MW appt and she found the heartbeat on the Doppler immediately. I’m quite tired, but much of that is probably (SEND) mum life!

Meadowfinch · 21/08/2025 13:08

I had ds at 45y2m.

Positives for me - mortgage almost paid, career established, salary reasonable, savings in place. Much calmer and more confident due to my age.

Negatives - mostly people's judgey ill mannered comments.

The reality was I had an easy pregnancy (no nausea, just a bit tired). Natural birth at 40+6. A slow labour and needed help right at the end. A perfect ds weighing exactly 8lb, now 17yo.

Despite becoming a single mum when ds was 3 (my decision), raising him has been easy. He was an easy happy child, and I negotiated childcare etc without many issues.

My only age related action - I had an amnio when my downs risk was calculated as 1:25.

Onthebusses · 21/08/2025 13:26

MinPinSins · 19/08/2025 06:50

If you get pregnant, there is around a 53% chance you'll lose it, as per the NHS, and a 1/30 chance the baby will have Down Syndrome. The chance of the incompatible with life trisomies (13/18) is much higher too.

It's slightly concerning you are considering this at 45 without knowing the huge impact age has on the likelihood of the baby having a chromosomal abnormality. Having said that, at that age, you would be offered thorough testing (and if you weren't, it would be worth every penny to do a private NIPT), and if you do manage to get and sustain a pregnancy, the baby is more likely to be healthy than not, despite the massively increased risk.

In terms of good news stories, remember that those that involve celebrities/influencers etc most likely involve either donated eggs, eggs stored when they were much younger or multiple rounds of IVF with PGT testing - making it a completely different ball game.

Those are baseline risks. My risk at 42 for a baby with a chromosomal abnormality was <1/400 on proper testing. Age of the man comes into play also. It's not higher risk just because you're older yourself.

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