Maternal Serum screened 1:8 for Down Syndrome

[Chris0102]

Hi All.. I'm (33 F) currently 17 weeks pregnant with my second baby. We live in Canada.

My 12th week ultrasound did not check for NT but the overall growth looked normal for the gestational age and the heart beat was good. I didn't have any concerning symptoms so far, no bleeding or abnormal blood pressure. I have also been feeling some baby movements for about a week and my fundal height measured appropriate for 16 weeks (last Doctor appointment).

However, I got a call from my doctor last Thursday informing that my numbers from prenatal screening requires further analysis. I have NIPT scheduled in another two days but we are really freaked out about the odds. Here is the screenshot of my results, 1:8 for Trisomy 21 and 1:100 for Trisomy 18.

Does the low PAPP-A of 0.14 and the HCG of 8.76 MoM mean that I should be directly looking for a Amnio ? or if I should wait for the NIPT results which may take another 2 weeks?

Hello I had a high Hcg of 3.33 and low papp_a of 0.13 I was one in 4 for downs and 1/50 for Edwards I had the cvs results as that was quick results had it done Thursday and got results back yesterday and all clear!! Worst wait of my life but I would rather know, it’s painless and yes 1% of miscarriage but I was told that’s if you move and it would happen there and then likely, scary but like I said I wanted to know and not be worried. I am now on asprin and extra growth scans

Hi .. thanks for sharing:) I'm still waiting to talk to my doctor to schedule me to Amnio.. I have NIPT and doctor's appointment scheduled tomorrow. I think the general practice here in Canada is to schedule for NIPT if the maternal serum doesn't look good but I feel the options should be discussed.