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Pregnancy

Talk about every stage of pregnancy, from early symptoms to preparing for birth.

My mother's pregnancy was high risk so mine has been classed the same.

10 replies

carrieND · 28/09/2023 15:39

I am only a few weeks pregnant (I'm 30 years old), but because my mother had me when she was 38, and her amniocentesis came back with a high risk of me having a genetic disorder, and me having a child with a genetic disorder, I have been classed as high risk. Mainly Downs Syndrome.
Has anyone been similar?
I don't know how they could test 30 years ago that I would likely have a baby with Downs Syndrome or another genetic disorder?

OP posts:
warmmfeet · 28/09/2023 19:26

I haven't had this but I guess some genetic disorders are hereditary so perhaps they are just being cautious. Try not to worry. As you say I'm not sure how truly accurate the tests were 30 years ago, or even 15 years ago etc.

Congratulations on your pregnancy!

ThomasinaLivesHere · 28/09/2023 19:38

I wasn’t asked any questions about my mum’s pregnancy so surprised that they knew something like that about your mum’s but like PP said it must have been something that can be hereditary for it to be noted.

thelonemommabear · 28/09/2023 19:46

I believe there is a form of Down syndrome which is hereditary Down syndrome - there are 3 types of Down syndrome - translocation Down syndrome is the one which can be hereditary

thecatsthecats · 28/09/2023 21:08

I am classed as high risk due to a combination of factors, only two of which could really be relevant, and all of which have been proven to be not having an effect on my pregnancy.

Some trusts will offer the high risk care pathway as a recommendation, not mandatory. And you're able to ask to be re-evaluated.

PinkRoses1245 · 28/09/2023 21:08

ThomasinaLivesHere · 28/09/2023 19:38

I wasn’t asked any questions about my mum’s pregnancy so surprised that they knew something like that about your mum’s but like PP said it must have been something that can be hereditary for it to be noted.

I was thinking the same, how do they even know?

thelonemommabear · 28/09/2023 21:18

@PinkRoses1245

If the amnio done on the OP before she was born identified that she had a translocation of the gene which usually causes DS (21) then that could be why

carrieND · 29/09/2023 09:34

Thanks for all your messages and info.
I remembered when my sister was pregnant 10 years ago my mum mentioned something to her but about me... It took a lot of GP digging but found on my medical notes saying "chromosomal abnormality - translocation".
But I'm still really confused as to how this would effect me as I was born without a genetic disorder. But I know if things are hereditary then I can carry a gene, but surprising how my mums pregnancy could have effected me this much.
I'm looking for more answers because I'm really stressed and the first scan on the NHS is a long time away...

OP posts:
carrieND · 29/09/2023 09:36

@thelonemommabear
Do you have more info on this?
I remember getting a blood test 10 years ago to check and was told everything is "normal"... But I wasn't pregnant at the time so didn't focus on how this would effect me now.
Thanks in advance!

OP posts:
thelonemommabear · 29/09/2023 16:19

You can carry the translocation for chromosome 21 which causes downs but it doesn't necessarily mean that you will have a child who has downs - I believe the risk in each pregnancy of having an affected child is around 12-15% (as opposed to around 1% if you aren't a carrier)

www.thetech.org/ask-a-geneticist/articles/2016/balanced-translocation-down-syndrome/

Sounds odd that you had it confirmed by amnio before you were born but then had a blood test which came back clear? You would have had to specifically had a karyotyping blood test 10 years ago - it's not a test routinely ordered by a doctor and not something that would just be routinely picked up in another blood test you might have had

Unless your mum had the blood test and was confirmed as the carrier but you are in fact not a carrier of the balanced translocation for chromosome 21

ConfessionsOfAMumDramaQueen · 29/09/2023 16:28

Family medical history comes up a lot. My pregnancy I was 'high risk' for low foetal birth weight and preeclampsia ... because my mum had preeclampsia in only one of her 4 pregnancies (her last at 40, I was 30 and had low blood pressure). Any history of diabetes in your family you'll be referred for testing. Blood clots in family? Blood thinners for you!

Often seems they take even the slightest risk to babies health before they're born much more seriously than any adults health.

You have a genetic history which means increased chance of a baby with Down's.

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