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Talk about every stage of pregnancy, from early symptoms to preparing for birth.

Too much Anti D Injection? Will it harm baby?

5 replies

Lou234 · 15/12/2022 09:32

Hi everyone,

I am rhesus negative and baby is rhesus positive so unfortunately I have to have the anti D injection.

I have already had it at 13, 15 and 24 weeks because of some bleeding/spotting( I am 27 weeks now).

They took my blood before the injection at 24 weeks and they rang me up yesterday to let me know they found anti D antibodies (A small amount). The lady was lovely and reassured me that it is most likely left over from the injections I had at 13 and 15 weeks but they are going to take my blood every 2 weeks now just in-case.

My worry now is that I have had too much of the anti D injection? I do not understand how it works, if they inject me with artificial antibodies do these not cross the placenta and harm the baby? I obviously had 2 does quite close together at 13 and 15 weeks.

I am due my routine dose next week and now I am worried about it.

I will ofcourse bring all this up to my midwife at my next appointment but I just wondered if anyone can share their experiences or share any knowledge on how it works.

Thank you 🙂

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CristinaNov182 · 03/03/2023 18:48

No, it doesn’t do any harm to the baby.

The injection acts on your blood and stops these antibodies from forming.

www.nhsinform.scot/healthy-living/screening/pregnancy/your-blood-count-blood-group-and-rhesus-status

how has it been for you and baby since? Just discovered I have antibodies too.

RugbyGirl1 · 03/03/2023 22:44

Hey @Lou234 I'm in almost exactly the same situation! I'm 29+5 and had my fifth anti-D this week (routine 28 week one but late) having had my fourth anti-D on Monday for minor spotting and also going for blood tests every other week for monitoring. I'm also ridiculously difficult to get blood out of so when going in for anti-D shots it tends to take hours - getting the blood done then waiting for the injection!

As @CristinaNov182 said, it doesn't harm the baby, it just stops your body from producing it's own antibodies.

Lou234 · 04/03/2023 09:23

I am 39 weeks now and been going for blood tests every other week, the anti body levels have dropped more and more each time and are now at a 0.1 something so I'm not too worried anymore 😊 just waiting for baby to come now!

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Lou234 · 04/03/2023 09:25

Its such a pain having to have blood taken constantly! My anti body levels keep falling so I'm not too worried anymore! I had my blood test on Wednesday and I am now 39 weeks so hoping it'll be the last time!

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CristinaNov182 · 06/03/2023 15:59

I talked to the midwives and I understand there is no issue for the current pregnancy/baby but there mig be /will be some for future pregnancies. I don’t plan to have more children, will have 2 now, so it doesn’t matter to me.

but what they have said that worries me now is that now the risk is to myself. If I need a blood transfusion during labour, I will need special blood that has these antibodies and it might take time to find some.

also there is a risk that I will have this for life and I will need to carry a blood transfusion card with me at all times… though they said this might clear out or based into he further tests they sent the blood for, I won’t . This part is not clear to me yet and I will discuss it with my consultant this week.

has anyone been in this position?

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