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Pregnancy

Talk about every stage of pregnancy, from early symptoms to preparing for birth.

Anti M antibody

6 replies

sophied1983 · 22/03/2021 18:53

Has anyone else been told they have these in their bloods? I received a letter today. A quick look on Google has scared the life out of me.

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rosiegal · 22/03/2021 20:22

Yes I did with my first pregnancy, currently 29+3 with my second but they haven’t showed up in my bloods this time. In my case it really was nothing to worry about, once it was picked up I had bloods taken every month and once I’d given birth I think they sent my sons blood to be checked at our nearest specialist hospital but that was it. My pregnancy and delivery were completely normal and there were no after effects observed in my son

sophied1983 · 22/03/2021 21:12

From what I have found online, sounds like it could be linked to the transfusion I had with my first.

Reassuring to know it didn't get in the way of your pregnancy/ delivery.

It has taken us 2.5yrs to get pregnant and a miscarriage - has left me so sensitive to anything going wrong. Burst into tears earlier.

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AlexaStop · 22/03/2021 21:15

Hi, there is a very informative Facebook group called support for antibodies in pregnancy. You will find lots of knowledge and support on this page.

I had antibodies too and knew very little until I joined the group.

AlexaStop · 22/03/2021 21:22

Posted too soon.
I had anti d, c and g. Baby spent 4 days on lights for jaundice and took folic acid for 12 weeks, and made a full recovery. I was induced at 37 weeks.

Some antibodies are worse than others, I'm sorry I don't know about anti M as there are so many.

Desmondo2021 · 22/03/2021 21:22

I had 3 x Anti K pregnancies which are potentially a similar issue despite being a different antibody. Escalating severity in each pregnancy, requiring 5 prenatal intrauterine transfusions by pregnancy number 4. Highly managed pregnancies but healthy if not a little but tiny and premature babies.

Ohthereyouarepeter · 22/03/2021 21:53

Hi
I work in blood transfusion and I wouldn’t worry too much about the Anti-M, it is unlikely to cause problems. Ii haven’t seen a case where Anti-M has caused HDFN as it is very rare. If you have a ‘warm-reactive’ anti-M then they may wish to test your partners genotype to see what chance your baby has of being M+ (Cold-reactice Anti-M antibodies do not cause any problems). Your blood will be retested at 28 weeks, then at delivery your sample and a cord sample from baby will be sent to the lab for testing. The cord sample will confirm whether baby is M+/M- and check the direct agglutination test (DAT). If baby is M+ And/or has a positive DAT they will be monitored for haemolysis/jaundice.

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