I'm self employed. I became self employed after I had my baby. I found that some days, I could get some work done while my baby took naps, but don't count on it. I generally relied on my partner getting home and taking over so I could do a few hours. But he doesn't have boobs, so it didn't work all the time.
As my workload increased and our son got older, it became unworkable, so I put him in nursery 3 afternoons a week. I've now increased it to 4. Somehow, we got to 2 years, but I've now idea how. DP and I were pretty frazzled by that point.
Bear in mind that you might qualify for tax free childcare. I think you need to earn £150 something a week. If I'd known this before, we would have started nursery a lot earlier. For every £80 you contribute, you get a £20 contribution from the government. So my childcare, from 1pm to 6pm, 4 days a week, comes to around £325 most months, which to me isn't the earth, but it enables me to get things done.
I do have busy weeks and DP takes DS out for the day at the weekend to let me get things done, but I try and avoid it as it's important we all get some quality time together. Sometimes it's unavoidable though.
I'm now pregnant again. Luckily, we should qualify for free hours for our son when he turns 3 in September. For DC 2, we'll be playing it by ear, but I think it's a safe bet we'll be starting childcare a lot earlier. Probably around 6 months.
If I had my time over, I would definitely have started childcare a lot earlier. Nevertheless, we're doing pretty well and our son is happy and settled. My advice would be not to expect to be full time without childcare - otherwise you'll never see your partner - and probably don't wait until 2 before you get childcare. We were tearing our hair out by that point and it was completely unnecessary.
Good luck with what you decide.