Hi Im just wondering if anyone else has been taking ondansetron and has felt really wierd on it? I have had severy nausea for the last 6 weeks now (I'm 11 weeks tomorrow) I have a very strong stomach so usually even if I have food poisoning I don't throw up so in my first few weeks I didn't vomit but the nausea was constant and unbearable. Then at around 9 weeks I started vomitting every couple of days and I have found after I vomit I get a good few hours releif from the nausea. Unfortunately to get to the stage where I actually vomit I have 4-6 hours of even worse nausea than usual and lots of dry heaving etc before anything actually comes up. My doc prescribed me ondansetron because I have to work full time and couldn't function so I've been taking that since about week 6 but after I threw up late night I didn't take my tablet and felt OK (not amazing but not crippled wih nausea all night ). I had been getting a weird feeling as though my body was crammed full of something (only way I can describe it) and I had thought this was just part of the MS but after a day and night off the ondansetron ilthat feeling seems to be easing although I still feel a but queasy. Sorry for the essay but my question is do you think that the ondansetron was stopping me from.vomitting when my body actually needed to vomit and giving me that awful crammed full feeling? Anyone else had this?