i did the Nuchal testing at 11 weeks and was glad i did. It's not a categorical positive or negative but my results were so low risk i was happy with that.
I assume you're referring to the amniocentesis?
if you want to do it, do it, rather than spending the rest of your pregnancy worrying about it. I was so glad to be able to 'draw the line' under it. If my results were 'high risk' i would have gotten the more invasive testing, such as the CVS, which can be done 3 weeks earlier than the amnio.
it's such a personal thing, do what your gut tells you.