Clexane although blood clotting results inconclusive

[ALittleLemonTwist]

Hi ladies

Wasn't quite sure where to put this. I've had 3 early m/cs amd have had various tests (mostly for hormones and clotting). Most of my tests have come back ok but one showed that I could have lupus. My consultant thinks that even though we do not know whether or not I have lupus (or any blood clotting disorder), I should be on baby asprin and clexane for the next pregnancy with no need for further testing.

Has anyone been in the same situation and gone on to have a healthy pregnancy? ie. taken clexane without knowing for certain if you suffer from blood clotting issues? I've searched for previous threads but it seems clexane is largely prescribed when a definitive blood clotting disorder has been diagnosed.

Any advice / positive stories would be greatly appreciated!!

TIA

Hi

I am in a similar situation. 2 early mcs. 4 sets of clotting tests inconclusive - protein c was high in one and protein s high in the other. i am taking aspirin. asked my obst about this and he said no point doing any more tests as clotting factors change during pregnancy. he didn't suggest any other blood thinner. also said that aspirin had little effect on the placenta. will quiz him more about that at next apt.

Thanks sh77. Wish I asked more at the appt yesterday. Always the way though and I find it all a bit of a minefield to be honest!

I think docs are slow to offer info unless you push them. I tend to do some reading about things that are bothering me before my app and then quiz them.

I think one risk of taking thinners if there is no clotting disorder is excessive bleeding during labour. In my first preg, my placenta stopped functioning properly towards the end (quite common) but with the 2 mcs, I worry about clots on the placenta.

Hope all works out well for you.

I think i took it acts I had emcs with ds. Is it the self administered injection of blood thinners to prevent clotting?
Anyhow they had no reason to suspect I had a clot it was apparently standard practice after surgery. Just thought I'd throw that into the mix

Hi littlelemon. I had 3 MCs as well. I am sorry you've had the same horror.

I had tests and they all came back clear (no suggestion of lupus or anything) and no hint of blood clotting issues or hormone imbalance.

Even though they were clear, the prof I was seeing put me on clexane (and also on cyclogest - which is a progesterone supplemnent) and told me I'd need to take it until 12 weeks.

He said that there is no harm in taking them and that a recently discovered side effect of clexane is that it promotes placental cell development (which has to be a good thing ).

I was only on it in the end for a couple of weeks because I had a couple of big bleeds and he thought that the Clexane was probably making it more traumatic for me because (once the bleeding started) I was bleeding more than I would otherwise.

Anyway, I have no idea whether the Clexane and/or Cyclogest made any difference at all (and neither does the prof) but I am going to be 35 weeks tomorrow and all seems to be going well. Fingers crossed

I hope that helps put your mind at rest - do ask your doc though.

Mrsflux - thanks for replying. Yes, it's the self administered injection so guess it could be same thing that you had?

kfw so sorry you have also had 3 mcs but lovely to hear that things going well with this pregnancy Thanks for posting - it's really put my mind to rest - it's so reassuring to read positive stories

Hi littlelemon :)

have they tested you for antiphospholipid syndrome? (they probably have) - I have it and am pregnant, being treated with clexane and baby aspirin. Antiphospholipid syndrome (APS) is a common cause of recurrent miscarriage. People with lupus often have it, but you can have it without lupus, like me. The diagnosis is a positive for lupus anticoagulant (a little confusing as a positive doesn't mean a positive for lupus!!) More info on www.hughes-syndrome.org

Good luck :)

good luck to you littlelemon. oh - and in case you wanted to know, mine were the self-administered injections too. (another positive side effect was that i no longer have a needle phobia!)

positive vibes.

I was given clexane to self administer as I had really severe SPD and had to be on bed rest for most of the pregnancy from about 17weeks.

Not the same as you but I obviously had no clots/ clotting issues was just given it as a precaution to stop me from getting clots due to immobility.

I now have a perfectly health and beautiful DD 7 weeks old.

Hope this helps. X

Thanks for all the replies - feeling much more positive now!

DancingCat Yes, they tested for APS but that came back negative. Hope you are having a good pregnancy

I now need to get my head around giving myself daily injections (although my DH has said he is more than happy to do it for me....a bit too enthusiastically for my liking. Clearly I have married some sort of sadist

Good luck ladies - hope all goes well for you all.

A LittleLemonTwist, I stopped Clexane at 34 weeks. No reason to take apart from recurrant IVF failure and my IVF doctor was keen to keep patients on it because of placental development benefits. First pregnancy got DH to do it until about 20 weeks and then just did them myself. Be brutal - jab in like a dart and then plunge steadily but fairly quickly. It hurts less and bruises less. I always wondered why I bruised mmore at the beginning and it was because I was dithering. Also, sometimes worth gently prodding your planned injection spot with the needle before you go in. Some spots are more sensitive than others for some reason, so if it doesn't feel right you can just move a centimetre or so.

i had borderline clotting issues (not lupus) and was advised to take 150mg aspirin and daily claxane injection.

am now 26 weeks pg after 4 recurrent mc.

no idea if it's the reason this one has stuck or not, but it s=certainly hasn't harmed.

i was only on the injections until 13 weeks.

all the best with your next pg.