Ok, so I'm no Jennifer Aniston, but other than that, it's spookily similar.
DH and I got Jackson, our crazy Weimaraner before we had kids; she was our baby. We loved her to pieces - totally untrainable, and a complete liability, but we loved her anyway.
She would put her snout on the bed whilst we were, ahem, doing it, just like in the film. And she would terrorise anyone who tried to house sit, like in film.
Then we had our first kid. Then our second. Then I started screaming at the dog. Just like in the film.
Even the non-dog related bits are parallel -- DH thinking he has given up his youth; me thinking I have given up being me to be a mum. The way DH totally fucked up his reaction on hearing I was pregnant - just like Owen Wilson did.
Moving to a completely new home; the dog becoming a part of the family again, rather than a nuisance.
I swear, I must be Jennifer Aniston in another life.
I think you have to be a dog lover, and mother of multiple kids to get this film, but I totally get it. Every time I want to send Jackson to the glue factory, DH says "come here Marley" to her and I feel bad.