I have a boy and a girl, both in their teens. My experience of the differences so far is:
Baby boys occasionally pee in your face during nappy changes.
You get an extra couple of years before puberty kicks in if you have a boy
The main other things are to do with balancing social pressures, so with my daughter, I spend more time encouraging her to take risks, speak out, fail with confidence etc because she's faced a lot more pressure to be perfect, and with my son I put more emphasis on using his physical and social strength wisely, and on expressing emotions.
But if I were describe their main interests and activities, it would be hard to allocate them to the boy or the girl:
Loves computer games to an almost obsessive extent, very into cute animal memes, plays a rough contact sport, likes cooking, loves art, watches YouTube videos about science/craft/makeup, plays a non-contact team sport, plays a musical instrument, likes climbing trees, plays dungeons and dragons, distinctive sense of style, doesn't care about clothes unless they are comfortable.