We've used reusables with both our boys (DS1 is 3.7 so only has one on at night now, although he doesn't need it, but likes to wear it 'just in case' and DS2 is 23 months). It's been great - the same set of nappies has done fine for both boys, although we've added a few extra night nappies and some newer 'plastic pants' along the way so feel it's been excellent value for money.
I went on www.thenappylady.co.uk and filled out her questionnaire to get advice; found it really useful and then chose what to buy from her recommendations (you're not committed to buying from her, although I did).
We have two types of nappies:
For day nappies, we use Teddy Nappies (we have these in both size 1 and size 2) with Motherease covers (Rikki wraps for when they're little as they're velcro fastening and Airflow which are popper fastening for when they're older).
For night nappies, we use either Motherease Sandy's or Bumbles with the same Motherease covers.
The Teddy Nappies come with boosters and we add a reusable liner. The Sandy's are thicker but we add a separate booster and liner as we use them at night. The Bimbles come with a clip in booster and we add another as we only use them for night. We did get disposable liners to try but they felt a bit rough so we just use reusable ones.
To be fair, we did use disposables for the first week or so with DS1 as I was in hospital for quite a while the first time as I had a c-section and transporting dirty nappies home for cleaning and back again would have been too complicated. With DS2 I had a c-section too and we only used disposables for a very short while before moving over to the reusables as I was out much quicker.
How many you need kind of depends on how often you want to wash, how quickly the nappies you choose dry etc. I think we had something like 16 size 1 teddies, 11 size 2, 5 rikki wraps, 5 small airflow, 5 large airflow, 4 bumbles, some fleece liners and spare boosters. But I went with quite a lot as I didn't want to wash every day; you could easily get away with less.
We also use reusable wipes - find they're much better at cleaning bums than the wipes you buy in shops.
Any questions, just shout and I'll try to answer.
PS - there is nothing so cute as a tiny baby in a mahoosive fluffy reusable nappy 