Ugh. Housework. I hate it.
If you have a build up, could you pay for a cleaner to come and blitz it, so it will be easier to keep on top of? I know it will be £££ but it might be a good long term investment? Do you have anyone else in the house who can help?
DH as SAHP used to do all the housework as he has very high standards and I am a natural slattern (think leaving mugs to go mouldy
etc). Recently we swapped as he had to go back to work.
What I do to keep on top of it is - I have a rule that anything left on the floor is not for me to deal with (I can't anyway) so DCs pick up after themselves and DH empties bins and does heavy lifting like hoovering every day the freak . I have a big IKEA bag for bringing down washing (can't wait for a stairlift!) and do a couple of washes and tumble drys a day. We have quite a few DC but the upside is they're old enough to help. They pick up, dust and Hoover their rooms and DH changes the beds weekly. I wash up whenever I need to but leave the pots and Heavy stuff for DH. I pick a different room a day for example, clean the bathroom as much as I can on Monday, kitchen on Tuesday, lounge on Wednesday...we have a small house which also helps.if I'm having a flare up I don't do much and DH does it, but I feel guilty as he works long hours and looks after me and DC very well. He is also forever telling me to leave the cleaning to him but this may be my lack of skills in this area 
So in summary
I would recommend you pay or get someone to get it up to speed for you and then do any heavy or "beyond you" stuff regularly. If you can, throw money at it! Otherwise just do a little and often as much as you can. If I can keep the room where we spend the most time presentable it helps me to feel calmer. I have extendable feather duster things so I don't have to try and reach. I am also saving for a lightweight cordless Hoover. I buy the best cleaning products I can as they require less scrubbing/physical effort. I don't iron or hang stuff out, I use the dryer
I also have lever arm things on taps which makes life easier.